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Phase I clinical study of ABI-007 in combination with gemcitabine

Phase 1
Completed
Conditions
pancreatic cancer
Registration Number
JPRN-jRCT2080223124
Lead Sponsor
Taiho Pharmaceutical Co., Ltd.
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
completed
Sex
All
Target Recruitment
40
Inclusion Criteria

Has personally given written informed consent to participate in this clinical study
- Pancreatic adenocarcinoma histologically confirmed to be invasive ductal carcinoma
- Macroscopic examination shows that the primary pancreatic lesion has been completely resected
- Has undergone surgery for primary pancreatic tumor within 12 weeks before the start of study treatment
- Pancreatic cancer staging: T1-3, N0-1 and M0 by TNM classification (the seventh edition, proposed by UICC in 2009)

Exclusion Criteria

- History of treatment other than surgery (chemotherapy, radiotherapy, etc.) for the primary pancreatic tumor
- Grade 2 or higher peripheral sensory or motor neuropathy
- As judged by the investigator (subinvestigator), ineligible for entry into the study

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
safety<br>tolerability
Secondary Outcome Measures
NameTimeMethod
safety<br>efficacy<br>other<br>safety, treatment exposure and efficacy
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