Postoperative Delirium After Kidney Transplantation

Completed

• Conditions: Post-operative Delirium

• Registration Number: NCT05887076
• Lead Sponsor: Charite University, Berlin, Germany

Brief Summary

This project is a retrospective evaluation of the routine data of patients who underwent a kidney transplant at the Charité Campus Mitte between January 2015 and December 2019 (until the corona pandemic).

Detailed Description

Post-anesthetic complications such as delirium can occur in patients after kidney transplantation. We would therefore like to characterize pathophysiological changes after transplantation of the kidneys and, if necessary, gain diagnostic and therapeutic knowledge. The purpose is to study postoperative delirium after kidney transplantation.

Study Timeline

• Study Start: 2023-05-24
• Study First Submitted: 2023-05-24
• Study First Submitted QC: 2023-05-24
• Study First Posted: 2023-06-02
• Primary Completion: 2023-12-19
• Study Completion: 2023-12-19
• Status Verified: 2024-10
• Last Update Submitted: 2024-10-17
• Last Update Posted: 2024-10-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 362

Inclusion Criteria

• All patients 18 years and older who underwent kidney transplantation and who were admitted to Post-intensive care unit or to an Intensive care unit at the Campus Charité Mitte

Exclusion Criteria

• Incomplete data records of the parameters to be determined
• Underage Patients

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of delirium	2015 - 2019	Incidence of delirium is recorded from validated delirium scores.

Secondary Outcome Measures

Name	Time	Method
Severity of delirium	2015 - 2019	Severity of delirium is recorded from validated delirium scores.
Delirium treatment	2015 - 2019	Delirium treatment is recorded peri-operatively.
Anesthesia	2015 - 2019	Anesthesia is recorded from patient files of patients with delirium.
Intraoperative parameter	2015 - 2019	Intraoperative parameter are recorded from patients with delirium.
Immunosupressive therapy	2015 - 2019	Immunosupressive therapy is recorded in patients with delirium.
Anesthesiological parameters	2015 - 2019	Anesthesiological parameters are recorded from patient files of patients with delirium.
Mortality	2015 - 2019	Mortality is measured within the hospital
Duration of delirium	2015 - 2019	Duration of delirium is recorded in days.
Intensive care unit stay	2015 - 2019	Length of intensive care unit stay is measured in days.
Hospital stay	2015 - 2019	Length of hospital stay is measured in days.
Pain teatment	2015 - 2019	Pain treatment is recorded peri-operatively.

Trial Locations

Locations (2)

Department of Anaesthesiology and Intensive Care Medicine CCM, Charite - Universitätsmedizin; 🇩🇪 Berlin, Germany

Medical Clinic with a focus on Nephrology and Internal Intensive Care Medicine; 🇩🇪 Berlin, Germany