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Clinical Trials/NCT04008758
NCT04008758
Recruiting
Not Applicable

Evaluation of Efficacy of Recruitment Maneuver Using Lung Ultrasound in Trauma Patients

Ajou University School of Medicine1 site in 1 country70 target enrollmentAugust 1, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Recruitment
Sponsor
Ajou University School of Medicine
Enrollment
70
Locations
1
Primary Endpoint
arterial oxygen partial pressure / fractional inspired oxygen ratio at end of surgery
Status
Recruiting
Last Updated
3 years ago

Overview

Brief Summary

In trauma patients, the incidence of pulmonary contusion is frequent. Recruit maneuver using lung ultrasound could be improve oxygenation in trauma populatioin, howevere, there is no previous study. The aim of this study is evaluation of the efficacy of lung recruitment using ultrasound in perioperative period in trauma patients.

Detailed Description

In trauma patients, the incidence of pulmonary contusion is 17-75%. Pulmonary contusioin leads to atelectasis, lung consolidatioin. Finally it could results acute respiratory distress syndrome. Lung ultrasound is non-invasive and available in anytime even during surgery. Previous studies showed recruitment maneuver using ultrasound improved postoperative oxygenation in pediatric cardiac surgery. In adults, recruitment maneuver not using ultrasound improved oxygenation after cardiopulmonary bypass. There is no study in adult trauma population. The aim of this study is evaluation of the efficacy of lung recruitment using ultrasound in perioperative period in trauma patients.

Registry
clinicaltrials.gov
Start Date
August 1, 2019
End Date
December 31, 2023
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Ajou University School of Medicine
Responsible Party
Principal Investigator
Principal Investigator

In-kyong Yi

Clinical assistant professor

Ajou University School of Medicine

Eligibility Criteria

Inclusion Criteria

  • Who need surgery under general anesthesia due to trauma
  • The position of the surgery is supine

Exclusion Criteria

  • Who has been ventilator care before the surgery
  • Thoracic surgery
  • Who had cardiopulmonary resuscitation
  • Who has acute respiratory distress syndrome

Outcomes

Primary Outcomes

arterial oxygen partial pressure / fractional inspired oxygen ratio at end of surgery

Time Frame: 2 hours

= P /F ratio; Smaller value respresents poor outcome Using arterial blood gas analysis the difference between baseline (immediate after intubation) and end of surgery : If P/F ratio difference is improved compared to baseline, it means recruitment maneuver is effective

Secondary Outcomes

  • Lung ultrasound score(2 hours)

Study Sites (1)

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