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临床试验/CTRI/2026/03/105837
CTRI/2026/03/105837尚未招募不适用

Acoustic comparison of speech in growing children with skeletal class II malocclusion before and after mandibular advancement using twin block appliance: an experimental study.

Dr. Jyoti Manchanda1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2026年4月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
30
试验地点
1

研究概览

简要总结

This study aims to evaluate the effect of mandibular advancement using the Twin Block appliance on the acoustic characteristics of speech in children with skeletal Class II malocclusion. Skeletal Class II malocclusion commonly caused by mandibular retrognathism may influence oral cavity configuration and potentially affect speech production. Functional appliances such as the Twin Block are widely used in growing patients to advance the mandible and improve jaw relationships. However limited evidence is available regarding their impact on speech acoustics.

This experimental before and after study will include children aged 10 to 14 years with skeletal and dental Class II malocclusion reporting to the Department of Orthodontics. Baseline records including clinical examination study models cephalometric radiographs photographs and speech recordings will be obtained before treatment T0. Participants will undergo mandibular advancement therapy using a Twin Block appliance. Follow up records will be obtained after completion of Twin Block therapy at 6 months T1 and again at 9 months from baseline T2.

Speech samples will be recorded in a quiet environment using a condenser microphone and analyzed using Praat software. Acoustic parameters including fundamental frequency F0 and formant frequencies F1 F2 and F3 for vowels a i and u will be measured. Cephalometric parameters and dental measurements will also be recorded to assess changes in craniofacial morphology and occlusion.

The study will compare acoustic speech characteristics before and after Twin Block therapy and evaluate the correlation between changes in speech parameters and craniofacial morphological changes following mandibular advancement treatment.

研究设计

研究类型
Interventional
分配方式
Na
盲法
Outcome Assessor Blinded

入排标准

年龄范围
10.00 Year(s) 至 14.00 Year(s)(—)
性别
All

入选标准

  • Clinically: a) Subject with a full cusp class II or end-on molar relationship bilaterally with convex facial profile.
  • b) Overjet more than 5mm.
  • c) Patients in whom clinical VTO (Visual treatment objective) improves with anterior positioning of mandible.
  • Radiographically: a) A pre-treatment cephalometric analysis with ANB angle more than 4 degrees with favourable functional analysis and favourable growth pattern.
  • b) Subjects who are in accelerated phase of pubertal growth spurt (MP3-FG and MP3-G stage).

排除标准

  • a) Subject who had a previous history of any orthodontic treatment b) Missing teeth, Supernumerary teeth, Presence of anterior open bite or cross bite c) Nasal stenosis due to structural problems.
  • d) Severe cognitive or communication impairments e) Currently in speech therapy or any history of speech therapy f) Syndromic or cleft lip and palate cases.

研究者

发起方
Dr. Jyoti Manchanda
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Jyoti Manchanda

Govt. Dental College and Hospital, Nagpur

研究点 (1)

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