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A study of haploidentical transplantation with post-transplant cyclophosphamide

Not Applicable
Recruiting
Conditions
AML,ALL,MDS,NHL,MM,CM
Registration Number
JPRN-UMIN000019089
Lead Sponsor
Department of Hematology, Kanazawa University Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
40
Inclusion Criteria

Not provided

Exclusion Criteria

1. Patients who are positive for HBs antigen, HCV antibody, or HIV antibody. 2. Patients with active other malignancies. 3. Women who are pregnant, of childbearing potential, or lactating. 4. Patients who experienced serious hypersensitivity or anaphylaxis to cyclophosphamide. 5. patients who are not eligble for this study at the discretion of the investigator.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
treatment related mortality within 100days
Secondary Outcome Measures
NameTimeMethod
1. overall survival, event free survival, relapse rate at 100 days 2. overall survival, event free survival, relapse rate at 1 year 3. neutrophilans platlet engraftment 4. engraftment failure 5. complete chimerism 6. acute GVHD 7. chronic GVHD 8. infectious event 9. grade 3-4 toxicity within 100 days
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