The effects of prenatal exposure to nicotine and cannabis on brain development at school age

Recruiting

• Conditions: gebruik van sigaretten en softdrugs tijdens de zwangerschap; brain development; consequences of cannabis use; 10042258

• Registration Number: NL-OMON35422
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 180

Inclusion Criteria

Prenatal exposure to nicotine or cannabis.
6 years old.
Informed consent by the parents.

Exclusion Criteria

Head trauma with loss of conscience
Presence of metal objects in or around the body
Not wanting to be informed of incidental findings

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary study parameters are intracranial volume, total brain volume,<br /><br>ventricular and lobar volume, grey and white matter volumes volumes of several<br /><br>subcortical structures, such as hippocampus and amygdala. Furthermore, we will<br /><br>measure cortical thickness and fractional anisotropy. Third parameter is the<br /><br>(standard) scores of the children on the various neuropsychological tasks.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable</p><br>