The Effect of Chewing Gum on Dry Mouth in Individuals With Diabetes Mellitus
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Improvement in dry mouth in individuals with diabetes
研究概览
简要总结
Dry mouth can seriously affect the quality of life of individuals because it affects chewing and swallowing functions. One of the diseases in which dry mouth occurs as a side effect of many diseases and/or treatments is diabetes mellitus. The aim of this study was to determine the effect of chewing gum on dry mouth in individuals with diabetes mellitus.
详细描述
Diabetic autonomic neuropathy and microvascular changes in the oral mucosa are thought to cause decreased salivary secretion in individuals. Furthermore, poor blood glucose regulation and the accompanying polyuria can cause dehydration, leading to dry mouth and decreased salivary secretion. Decreased salivary secretion and subsequent changes in the oral mucosa have been reported in diabetic individuals with poor glycemic control.
Chewing gum is one of the activities that increases salivary secretion. It affects salivary pH and flow rate through both taste and mechanical stimulation, relieving dry mouth symptoms in individuals. While the unstimulated salivary flow rate in humans is 0.3 ml/min, this rate can reach 7 ml/min in someone chewing gum. Due to these known properties, chewing gum can be beneficial for dry mouth in individuals.
Literature reviews have shown that chewing gum reduces the feeling of dry mouth, increases salivary secretion, and quenches thirst. It is also believed that increased salivary secretion dilutes the bacterial load in the mouth, thus reducing the risk of periodontal disease. It is anticipated that chewing gum may be a factor that can improve the quality of life for patients with chronic diseases that require fluid restriction and a special diet. A review of the literature found no studies demonstrating the effect of gum chewing on dry mouth in individuals with diabetes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The inclusion criteria for individuals in the study were; being diagnosed with type 2 diabetes mellitus, having an HbA1c value of 7% and above, being able to communicate verbally, not having hearing loss, and accepting the voluntary consent form voluntarily.
排除标准
- •The exclusion criteria for individuals to be included in the study were having additional diseases that caused dry mouth and oral problems and/or using medication or other treatments for this reason (chemotherapy, radiotherapy, Sjögren syndrome, patients who cannot communicate verbally, have hearing problems, do not want to chew gum, use of antihypertensive, anxiolytic and diuretic drugs).
研究组 & 干预措施
Intervention Group
The intervention group was informed about the study. Dry mouth was noted at baseline. Individuals in the intervention group were asked to chew sugarless gum for 15 minutes before meals and before 3 main meals for 7 days.
干预措施: Chewing gum (Other)
Standart Therapy Group
Patients in the control group were also informed about the study and completed a data collection form via face-to-face interview. No interventions were performed on the control group patients. They were also informed that they would be re-evaluated one week later during the study and were asked to refrain from chewing gum during this period.
干预措施: Standart therapy group (Other)
结局指标
主要结局
Improvement in dry mouth in individuals with diabetes
时间窗: 5
The level of dry mouth of the individuals before and after the intervention was defined by the Xerostomia scale. The scale consists of 11 questions. The lowest possible score is 11 and the highest is 55, with higher scores indicating increased dry mouth.
次要结局
未报告次要终点
研究者
Saadet Aybek,
Clinical Nurse
Çankırı Karatekin University