Registry of COVID-19 Patients at AOUI Verona
- Conditions
- Coronavirus Disease 2019
- Registration Number
- NCT04497194
- Brief Summary
The registry of COVID-19 patients was designed to collect epidemiolgical, demographic, clinical, anamnestic and outcome information together with serological and microbiological samples from COVID-19 patients admitted at the University Hospital of Verona (Azienda Ospedaliera Universitaria Integrata, AOUI Verona). All SARS-CoV 2 positive patients admitted and able to give an informed consent are included, irrespectively of age and gender.
- Detailed Description
Anamnestic data are collected at the enrollment, while all the other clinical and epidemiological information are retrieved retrospectively from patients' medical records and electronic health records.
Serological and microbiological samples (blood samples, fecal samples and nasal/rectal swabs) are collected within 48 hours after admission and during the hospital stay, according with routine internal procedures.The biological samples are stored at the University Laboratory for Medical Research (Laboratorio Universitario di Ricerca Medica, LURM).
A dedicated database has been created and implemented to collect all the above mentioned information.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 430
- PCR for SARS-CoV 2 positive on NPS swab or high suspicion of SARS-CoV 2 with ongoing swab;
- All ages;
- All genders;
- Informed consent obtained.
- Failure to obtain the informed consent.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Arterial blood gas anaysis pH in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months pH
Blood pressure (mmHg) on admission in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months Blood pressure (mmHg)
Respiratory rate (breaths per minute) on admission in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months Pulse rate (beats per minute)
Peripheral oxygen saturation (%) on admission in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months Peripheral oxygen saturation (%)
Body temperature (°C) on admission in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months Body temperature (°C)
Lymphocytes (cell/mm3) in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months Lymphocytes (cell/mm3)
L-lattato deidrogenasi (LDH, mU/ml) in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months LDH (mU/ml)
Creatine kinase (CK, U/L) in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months CK (U/L)
Epidemiological predictors of poor outcomes in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months Epidemiological data including demographic data, contact with COVD-19 positive patients and onset of symptoms.
C reactive protein (CRP, m/gL) in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months CRP (m/gL)
Clinical predictors of poor outcomes in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months Underlying chronic diseases, signs/symptoms related with COVID-19 diseases an clinical presentation on admission
Pulse rate (beats per minute) on admission in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months Pulse rate (beats per minute)
Platelets (cell/mm3) in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months Platelets (cell/mm3)
D-dimer (μg/L) in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months D-dimer (μg/L)
ferritin (mcg/L) in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months ferritin (mcg/L)
Creatinine (mg/dl) in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months Creatinine (mg/dl)
Procalcitonin (PCT, ng/mL) in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months PCT (ng/mL
Neutrophils (cell/mm3) in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months Neutrophils (cell/mm3)
AST (U/L) in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months AST (U/L)
Arterial blood gas anaysis HCO3 (mmol/l) in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months HCO3 (mmol/l)
White Blood Count (WBC, cell/mm3) in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months White Blood Count (WBC, cell/mm3)
fibrinogen (g/L) in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months fibrinogen (g/L)
ALT (U/L) in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months ALT (U/L)
Arterial blood gas anaysis pO2 (mmHg) in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months pO2 (mmHg)
Virological factors associated with the pathogenesis of COVID-19 through study completion, an average of 3 months Nasal and rectal swabs, fecal samples and blood samples
Arterial blood gas anaysis pCO2 (mmHg) in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months pCO2 (mmHg)
Arterial blood gas anaysis SpO2 (%) in COVID-19 patients admitted to University Hospital of Verona through study completion, an average of 3 months SpO2 (%)
Host-related factors associated with the pathogenesis of COVID-19 through study completion, an average of 3 months IL-6 (pg/mL)
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University Hospital of Verona
🇮🇹Verona, Italy