A double-blind, randomized controlled pilot study of olive leaf extracts(OLE) for the prevention of periodontal diseases.
Not Applicable
- Conditions
- Periodontal diseases
- Registration Number
- JPRN-UMIN000005309
- Lead Sponsor
- Department of Preventive Dentistry, Osaka University Graduate School of Dentistry
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 45
Inclusion Criteria
Not provided
Exclusion Criteria
Those who took periodontal surgical therapy within 6 months Those who are pregnant or lactating Those who have a history of systematic diseases Those who took antibiotics within 3 months Those who took anti-inflammatory drugs within 2 weeks Those who have unrestored caries Those who smoke within 6 months Those who participate in other clinical trial Those who are judged not eligible for the study subjects by their investigators
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Probing pocket depth(PPD), Gingival index(GI), Bleeding on probing(BOP)
- Secondary Outcome Measures
Name Time Method Remaining teeth, Clinical attachment level, Plaque index, Cytokines in GCF