A study for optimized acupuncture protocol in the prevention and treatment of migraine

Phase 1

Recruiting

• Conditions: Migraine

• Registration Number: ITMCTR1900002333
• Lead Sponsor: Shuguang Hospital affiliated with Shanghai University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. It meets the diagnostic criteria for migraine without aura in the International Classification of Headache Disorders, 3rd Edition, developed by the International Headache Society (IHS) in 2013.
(1) At least 5 times of headaches meeting the standard B-D;
(2) Attack lasts for 4-72h (untreated or ineffective);
(3) Headache has at least 2 of the following 4 characteristics:
1) unilateral distribution;
2) pulsation;
3) moderate or severe pain;
4) daily activities lead to increased headache or headache leading to limited daily activities (such as walking or landing).
(4) At least one of the following items in the onset of headache: ? nausea and/or vomiting; ? photophobia and phobia;
(5) Cannot be better explained by another diagnosis of headache disease in ICHD-3;
2. Aged 20 and 65 years;
3. In the attack period, the seizures are more frequent, and the monthly seizures are = 2 times or = 4 days each time;
4. Preventive drugs that did not use any migraine within 3 months prior to the study;
5. A more frequent, prolonged or uncomfortable aura;
6. Those who signed the informed consent form.

Exclusion Criteria

First part:
1) Those who have long relied on analgesics;
2) Patients with diseases such as the nervous system and circulatory system are combined;
3) Patients during pregnancy and lactation;
4) An intracranial organic disease was found after examination;
5) Patients participate in other clinical trials;
6) Those with a history of long-term depression;
7) Those with electroacupuncture and acupuncture contraindications.
the second part:
1) Same as Part one;
2) Those who have metal residues in the body, deep vein catheters, etc. cannot perform MRI scan or affect image quality.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Headache level;The number of days the headache occurred;

Secondary Outcome Measures

Name	Time	Method
MIDAS;