NL-OMON35095CompletedNot Applicable
Autoimmunity in Chronic Obstructive Pulmonary Disease - Autoimmunity in COPD
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 120
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18 to 99 (—)
Inclusion Criteria
- •COPD patients:
- •Clinical diagnosis of COPD
- •No allergies
- •Post-bronchodilator FEV1 < 80% predicted, and postbronchodilator FEV1/FVC<70%
- •Age > 40
- •Current or ex-smokers > 10 pack years
- •Ex-smokers have to have quitted smoking for at least one year
- •No other major current health problems
- •Written informed consent;Healthy controls:
- •No signs of pulmonary disease
- •No allergies
- •No other major current health problems
- •FEV1 > 90 % predicted and FEV1/FVC > 70%
- •Age > 40
- •Never smokers, i.e. no cigarettes last year, and < 5 pack years, or current smokers > 10 pack years; or ex- smokers for > 1 year and > 10 pack years
- •Written informed consent
Exclusion Criteria
- •Addiction to alcohol or drugs
- •COPD exacerbation in the 6 weeks preceding the study
Investigators
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