EUCTR2004-005043-97-GB
Active, not recruiting
Not Applicable
A Pilot study investigating the use of Intravitreal Triamcinolone prior to macular laser for Clinically Significant Diabetic Macular Oedema - CSMO and triamcinolone
St Mary's NHS Trust0 sites50 target enrollmentApril 5, 2005
DrugsKenalog
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Macular oedema affects 29% of diabetic patients and is the main cause of visual impairment. Previous studies show that diffuse macular oedema carries a particularly poor prognosis despite laser photocoagulation.
- Sponsor
- St Mary's NHS Trust
- Enrollment
- 50
- Status
- Active, not recruiting
- Last Updated
- 14 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\) Diabetes Mellitus
- •2\) Clinically significant macular oedema as defined by the ETDRS studies
- •3\) Visual Acuity worse than 6/12 (0\.3 LogMAR)
- •4\) OCT thickness greater than 300um
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range
- •F.1\.3 Elderly (\>\=65 years) yes
- •F.1\.3\.1 Number of subjects for this age range
Exclusion Criteria
- •1\) Retinal pathology other than that due to Diabetes
- •2\) Glaucoma, ocular hypertension or known steroid responder
- •3\) Previous laser treatment
- •4\) Only eyes
- •5\) Visual acuity better than 6/12
- •6\) Proliferative diabetic retinopathy
- •7\) Unable to attend for follow up
- •8\) Unfit for a local anaesthetic (LA) procedure
- •9\) Unable to consent fully
Outcomes
Primary Outcomes
Not specified
Similar Trials
Active, not recruiting
Phase 1
A Pilot Study Evaluating the Effect of Intravitreal Fluocinolone Acetonide (0.19mg) in Patients with Retinitis Pigmentosa.Retinitis Pigmetosa.MedDRA version: 19.0 Level: PT Classification code 10038914 Term: Retinitis pigmentosa System Organ Class: 10010331 - Congenital, familial and genetic disordersTherapeutic area: Body processes [G] - Genetic Phenomena [G05]EUCTR2016-002523-28-GBMoorfields Eye Hospital1
Recruiting
Not Applicable
Clinical study of the use of Bevacizumab in glaucoma surgery.RBR-9wkw73jnião Metropolitana de Educação e Cultura
Active, not recruiting
Phase 1
Intravenous iron in the management of anaemia in palliative oesophageal and gastric cancerEUCTR2013-000209-22-GBResearch and Development Nottingham University Hospital27
Completed
Phase 1
A pilot study evaluating the safety of intravenously administered human amnion epithelial cells for the treatment of hepatic fibrosiscirrhosisliver fibrosisOral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colonACTRN12616000437460Monash Health9
Completed
Phase 1
Amnion cells for the treatment of bronchopulmonary dysplasia in premature babiesACTRN12614000174684Monash Health Research Directorate6