Yoga for Rheumatoid Arthritis

Not Applicable

Completed

• Conditions: Osteoarthritis; Rheumatoid Arthritis
• Interventions: Behavioral: yoga

• Registration Number: NCT00349869
• Lead Sponsor: Johns Hopkins University

Brief Summary

The purpose of this study is to evaluate the impact of yoga on inflammatory arthritis and knee osteoarthritis.

Detailed Description

Yoga is a set of ancient Indian theories and practices, focusing on unifying mind, body, and spirit, and promoting strength, balance, and flexibility. The physical aspect of yoga includes poses, breathing techniques, and relaxation. Inflammatory arthritis, a chronic disease characterized by inflammation of the lining of the joints, can cause long-term joint damage, resulting in chronic pain, loss of function, and disability.

The primary objective of this study is to learn how people with inflammatory arthritis and knee osteoarthritis respond to an exercise program of yoga. To accomplish this, 30 persons with inflammatory arthritis or knee osteoarthritis will be randomly assigned to one of two groups. Group one will begin an immediate 8-week program of yoga classes consisting of 60-minute sessions, twice a week. Group two, or the "waitlist" control group, will receive 8 weeks of arthritis education followed by the same 8-week yoga program as group one. Participants also will have blood drawn, and complete various tests. The yoga classes will be taught by an experienced, certified yoga instructor, and are designed especially for the needs of people with inflammatory arthritis and knee osteoarthritis.

This study will provide important data on integrating mind-body activities into the treatment of inflammatory arthritis and knee osteoarthritis.

Study Timeline

• Study First Submitted: 2006-07-06
• Study First Submitted QC: 2006-07-06
• Study First Posted: 2006-07-10
• Study Start: 2006-08
• Primary Completion: 2010-08
• Study Completion: 2011-08
• Status Verified: 2023-06
• Last Update Submitted: 2023-06-14
• Last Update Posted: 2023-06-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

• Age 18+ (RA only upper age limit 70)
• Confirmed or probable OA (using pre-specified criteria) OR Rheumatoid arthritis (participation approved by rheumatologist)
• Currently sedentary (physically active for 20 min < 3times/week)

Exclusion Criteria

• Inability to ambulate without use of assistive device
• Uncontrolled high blood pressure or existing heart condition
• Co-morbid inflammatory condition with overlapping symptoms (i.e., fibromyalgia)
• Surgery within 6 months

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	yoga	8-week yoga program

Primary Outcome Measures

Name	Time	Method
Physical Health	baseline, post intervention, follow-up	Assessed using SF36 Physical Component Score

Secondary Outcome Measures

Name	Time	Method
Psychological Function	baseline, , posttest, follow-up	Change in SF36 MCS, CES-D, PANAS, Perceived Stress and Arthritis Self Efficacy
Mobility/Fitness	baseline, posttest, follow-up	Change in flexibility, balance, strength, walk time
HRQL	baseline, post intervention, follow-up	Change in SF36 domains
RA Disease Activity	baseline, post intervention, follow-up	DAS28 CRP score

Trial Locations

Locations (1)

Johns Hopkins Arthritis Center, 5501 Hopkins-Bayview Circle, Ste 1B.14; 🇺🇸 Baltimore, Maryland, United States