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临床试验/NCT02825303
NCT02825303已完成不适用

Mid-term Effect of a Novel Sit-to-stand Workplace (ACTIVE OFFICE) on Cognitive and Physiological Parameters

University of Applied Sciences Upper Austria2 个研究点 分布在 1 个国家目标入组 18 人开始时间: 2014年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
18
试验地点
2
主要终点
Daily sitting time

研究概览

简要总结

Prolonged sitting is a risk factor for cardiovascular and musculoskeletal diseases, diabetes, several types of cancer and all-cause mortality. In combination with static and awkward postures, the prevalence of musculoskeletal diseases can increase further. Although the implementation of sit-to-stand or active workstations can help to reduce sitting time, improve physical activity at work and promote health benefits, it might also lead to changes in cognitive functions such as productivity The purpose of this study is to evaluate the mid-term effect of a novel two desk sit-to-stand workplace on sitting time as well as physiological and cognitive parameters for healthy people of working age in comparison to their traditional workplace.

详细描述

Measurements were made both in the field and in a laboratory. Field measurements were made and processed continuously over the 23-week intervention period. Laboratory measurements were made on two different days, one day prior to intervention, and one day following intervention (due to cross-over design, each subject underwent 4 total days of laboratory measurements). Field measurements were collected automatically at the participants' workstation in their working office.

Laboratory tests were conducted in a controlled, simulated work-space located at the University of Applied Sciences Campus Linz. All laboratory measurements were made in a controlled laboratory at the campus site Linz of the University of Applied Sciences Upper Austria. Temperature, air flow, humidity, lighting conditions (artificial light only) and noise level were controlled and set to be consistent with the subjects' typical working environment.

During the laboratory measurements, subjects either stood or sat upright in an ergonomic office chair, according to the study protocol. Subjects were encouraged to work as fast and as accurately as they could. To ensure identical testing conditions between subjects and to not unduly influence physiological parameters such as salivary cortisol level or heart rate variability, subjects were required to minimize excessive movement (e.g. standing up during the sitting periods).

In the first (initial) phase, participants were familiarized with the study protocol. Sitting time and weekly physical activity were determined via the IPAQ-questionnaire. Examples of each cognitive test implemented in the cognitive phase were executed according to their guidelines. A 30 minute break in a sitting posture was used to ascertain baseline heart-rate and cortisol level. Baseline heart-rate was calculated after a 20 minute rest for a 5 minute interval and saliva samples were collected at the end (30min) of the break.

In the second (cognitive) phase subjects participated in a test battery containing five blocks. Each block consisted of a working speed test (text editing task), an attentional test (d2R-test of attention) and a reaction time test (Stroop-test). These tests lasted for 30 minutes to fulfill recommendations regarding postural changes. To simulate "common" working conditions (computer based and non-computer based tasks), digital (text editing task, Stroop-test) as well as pen & paper (d2R-test) versions of the implemented tests were used. All blocks were executed in alternating postures (sit - stand - sit - stand - sit) and at the end of each block - after a 5 minute break - salivary samples were collected. The order of posture was not changed within groups or time.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Prevention
盲法
None

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Healthy Caucasian (no acute or chronic diseases)
  • Normal weight or slightly overweight (BMI: 18.5 - 27.5 kg/m²)
  • Regularly working in sedentary office environments
  • Regular computer users
  • Fluent German speakers
  • Consented to participate

排除标准

  • Heavily overweight & Obesity (BMI > 27.5 kg/m²)
  • Short office stay duration (< 8 h / day or < 20 h / week)
  • Experience in sit-to-stand workstations
  • Acute or chronic diseases
  • Inability to stand
  • Visual impairments that had not been corrected
  • Color blindness
  • People planning to change their physical activity level
  • Regular smokers (> 1 cigarette /day)
  • Not consented to participate

结局指标

主要结局

Daily sitting time

时间窗: baseline and 23 weeks

Changes in sitting time after 23 weeks in the experimental group compared with its own control period and the control group. Measuring methods: International Physical Activity Questionaire (IPAQ); self developed tracking software at the participants' workplace

次要结局

  • Cognitive performance (composite outcome)(baseline and 23 weeks)

研究者

发起方
University of Applied Sciences Upper Austria
申办方类型
Other
责任方
Principal Investigator
主要研究者

Bernhard Schwartz

Research Associate

University of Applied Sciences Upper Austria

研究点 (2)

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