Periapical Lesions and Immediate Implants

Completed

• Conditions: Periapical Granuloma; Osseointegration Failure of Dental Implant; Dental Implant Failure Nos

• Registration Number: NCT06521203
• Lead Sponsor: Akdeniz University

Brief Summary

The aim of this case-control study is to evaluate the success and survival rates of dental implants immediately placed into extraction sites in the presence of periapical pathology.

The main questions it aims to answer are:

What were the survival and success rates of implants immediately placed into extraction sockets of teeth with chronic periodical lesions.

A retrospective analysis was performed based on the evaluation of certain clinical and radiographic parameters 12 months after prosthetic function of these implants.

Detailed Description

In 25 patients (13 men, 12 women), certain clinical and radiological parameters were retrospectively evaluated with particular interest in survival and success rates of the implants (total of 30 implants, 21 in the maxilla, 9 in the mandible) placed immediately to extraction sites of teeth with chronic periapical lesions. These parameters included mobility and the presence or absence of chronic pain, probing depth, gingival index, radiographic measurements of crestal bone loss on mesial and distal aspects of the implants.

Study Timeline

• Study Start: 2016-01-01
• Primary Completion: 2018-01-01
• Study Completion: 2023-12-01
• Status Verified: 2024-07
• Study First Submitted: 2024-07-17
• Study First Submitted QC: 2024-07-24
• Last Update Submitted: 2024-07-24
• Study First Posted: 2024-07-25
• Last Update Posted: 2024-07-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• To have 1 or more teeth with a chronic periapical lesion that requiring extraction.
• The chronic periapical lesion should be determined as an asymptomatic periapical radiolucency with a diameter ranging between 4 and 8 mm.
• The patients undergoing tooth extraction must have been treated with an immediate implant placement procedure.
• At the time of extraction and implant placement, the neighboring teeth must have had healthy periodontal and periapical status.

Exclusion Criteria

• Age younger than 18 years
• Any systemic disease or medication that might compromise osseointegration, bone or soft tissue healing
• Smoking
• Purulent exudate during the extraction
• Severe deficiency of soft and/or hard tissue in implant region
• Pregnancy
• Lactation
• History of chemotherapy or radiotherapy
• Severe parafunctional habits

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Survival of the implants	Immediately after the implant placement and after 12 months of prosthesis function.	Pain on palpation, percussion, or function (Yes/No) Implant mobility (Yes/No) Radiographic crestal bone loss (\<4.0 mm) Absence of pain and mobility and crestal bone loss up to 4 mm were regarded as survive.
Success of the implants	Immediately after the implant placement and after 12 months of prosthesis function.	Pain on palpation, percussion, or function (Yes/No) Implant mobility (Yes/No) Radiographic crestal bone loss (\<2mm) Gingival index score (1-2-3) Probing depth (mm) Absence of pain and mobility, crestal bone loss \<2mm, GI score less than 2, probing depth \<5mm were regarded as success.

Trial Locations

Locations (1)

Akdeniz University; 🇹🇷 Antalya, Turkey