To evaluate the effect of Time Lapse Imaging compared to Conventional Incubation System on the clinical pregnancy rate, early miscarriage rate and ongoing pregnancy rate
Not Applicable
- Conditions
- Health Condition 1: Z30-Z39- Persons encountering health services in circumstances related to reproduction
- Registration Number
- CTRI/2023/01/048823
- Lead Sponsor
- ONE
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Normo-responders defined as antral follicle count (AFC) 7-15
2.Diminished ovarian reserve- defined as antral follicle count (AFC)- ?6
3.Tubal factor
4.Mild male factor infertility defined as <15 M/ml, <32% Progressive motility and <4% normal morphology
Exclusion Criteria
Patients who were
1.Undergoing IVF for fertility preservation
2.Women >38 years of age
3.Polycystic ovarian syndrome
4.Severe endometriosis
5.Women with uterine factor infertility
•Severe male factor infertility- cases of severe OATS
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary objective: <br/ ><br>1.To compare the Clinical pregnancy rate between conventional incubation system and embryoscope group <br/ ><br>Clinical pregnancy rate defined as intrauterine gestational sac and fetal cardiac activity at 6 weeks <br/ ><br>Timepoint: 6 weeks
- Secondary Outcome Measures
Name Time Method Secondary objective: <br/ ><br>2. Proportion of good quality embryos at Day 3 <br/ ><br>3.Proportion of embryos undergoing blastulation <br/ ><br>4.Ongoing pregnancy rate- defined as presence of fetal cardiac activity at 12 weeks period of gestation <br/ ><br>5.Early miscarriage rate- defined as miscarriage at 4-12 weeks <br/ ><br>6.Cumulative pregnancy rate- after either one fresh and one frozen transfer or two frozen transfers, that is, after a total of two transfers <br/ ><br>Timepoint: Day 3 <br/ ><br>12 weeks