NCT06596863已完成不适用
Association of Serum Uromodulin and DKD a Systematic Review and Meta Analysis
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,774
- 试验地点
- 1
- 主要终点
- Association of serum uromodulin with DKD: asystematic review and meta analysis
研究概览
简要总结
Several studies have investigated the association between the changes of serum uromodulin and diabetic nephropathy (DN). However, the results are still controversial. Hence, this meta-analysis aimed to evaluate the association of uromodulin with DN.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Studies were included if they met the following criteria:
- •serum level of uromodulin was determined;
- •the samples were enrolled from diabetic patients;
- •mean ± SD was reported for uromodulin between patients with and without DN;
- •the level of albumin to creatinine ratio (ACR), glomerular filtration rate (GFR), or albumin excretion rate (AER) in patients with DN was determined
排除标准
- •Studies were excluded according to the following criteria:
- •duplicate studies;
- •review articles;
- •non original research articles;
- •studies with insufficient data to extract;
- •non-human research;
- •studies that determined urine level of uromodulin.
结局指标
主要结局
Association of serum uromodulin with DKD: asystematic review and meta analysis
时间窗: may, 2024
Evaluate the meta analysis of association of serum uromodulin in the 3 diabetic group comparing with each other and compare them to the control group and correlate these results with other kidney biomarker
次要结局
未报告次要终点
研究者
Shaimaa Ibrahim Barr
Dr of Biochemistry
Tanta University
研究点 (1)
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