Serum Uromodulin and DN Systematic Review and Meta Analysis
Completed
- Conditions
- Diabetic Nephropathies
- Registration Number
- NCT06596863
- Lead Sponsor
- Tanta University
- Brief Summary
Several studies have investigated the association between the changes of serum uromodulin and diabetic nephropathy (DN). However, the results are still controversial. Hence, this meta-analysis aimed to evaluate the association of uromodulin with DN.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 1774
Inclusion Criteria
-
Studies were included if they met the following criteria:
- serum level of uromodulin was determined;
- the samples were enrolled from diabetic patients;
- mean ± SD was reported for uromodulin between patients with and without DN;
- the level of albumin to creatinine ratio (ACR), glomerular filtration rate (GFR), or albumin excretion rate (AER) in patients with DN was determined
Exclusion Criteria
-
Studies were excluded according to the following criteria:
- duplicate studies;
- review articles;
- non original research articles;
- studies with insufficient data to extract;
- non-human research;
- studies that determined urine level of uromodulin.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Association of serum uromodulin with DKD: asystematic review and meta analysis may, 2024 Evaluate the meta analysis of association of serum uromodulin in the 3 diabetic group comparing with each other and compare them to the control group and correlate these results with other kidney biomarker
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Tanta Yniversity
🇪🇬Tanta, Yes, Egypt
Tanta Yniversity🇪🇬Tanta, Yes, Egypt