Study to Determine the Phototoxity of Atralin (Tretinoin) Gel, 0.05%
- Registration Number
- NCT00604032
- Lead Sponsor
- Coria Laboratories, Ltd.
- Brief Summary
To assess the potential of tretnoin gel 0.05% to produce phototoxic reactions, measured as skin reactions 24 and 48 hours after UV radiation of drug on skin.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- Normal healthy volunteers
- 18 years of age or older
Exclusion Criteria
- Less than 18 years of age
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description 1 Atralin (tretinoin) Gel, 0.05% -
- Primary Outcome Measures
Name Time Method UV induced skin sensitization 4 days
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie tretinoin-induced phototoxicity in healthy skin?
How does tretinoin gel 0.05% compare to other retinoids in phototoxic reaction profiles?
Are there specific biomarkers that predict phototoxic response to tretinoin in Phase 1 trials?
What adverse events are commonly associated with tretinoin gel phototoxicity in clinical settings?
What combination therapies with tretinoin have shown improved photoprotection in dermatological research?
Trial Locations
- Locations (1)
Suncare Research Laboratories
🇺🇸Winston-Salem, North Carolina, United States
Suncare Research Laboratories🇺🇸Winston-Salem, North Carolina, United States