The effect of vitamin D supplementation in patients with ulcerative colitis

Not Applicable

• Conditions: ulcerative colitis.; Ulcerative colitis, unspecified

• Registration Number: IRCT20100524004010N22
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 March 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Cases with Ulcerative colitis
Active mild to moderate disease severity
No evident affliction with other intestinal diseases or disorders, inflammatory diseases and infectious diseases
No history of taking supplements such as vitamin D multivitamin-mineral, omega-3, polyphenolic and antioxidants
Not taking anti-coagulation drugs such as Heparin and Warfarin or NSAIDs (Non steroidal anti-inflammatory drugs), antihistamines and calcium channel antagonists such as Nifedipine within the past month
Patients with vitamin d defficiency (less than 30 nano gram per mili liter)
Body mass index (BMI) over than 18.5 and less than 30 kg/m2
Tendency to participate in this research
No change in type & dose of drug usage during last month

Exclusion Criteria

Pregnancy or lactation in women or use of oral contraceptive drugs
The patient Unwillingness to continue participation in this research
Drug type and dosage change during intervention

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Simple Clinical Colitis Activity Index. Timepoint: At the beginning and at the end of the study. Method of measurement: Simple Clinical Colitis Activity Index Questionnaire (SCCAIQ).;Quality of life. Timepoint: At the beginning and at the end of the study. Method of measurement: Inflammatory Bowel Disease Questionnaire -9 (IBDQ-9).;TNF-a. Timepoint: At the beginning and at the end of the study. Method of measurement: ELISA.;Hs-CRP. Timepoint: At the beginning and at the end of the study. Method of measurement: ELISA.;Serum TOC. Timepoint: At the beginning and at the end of the study. Method of measurement: kit.;Serum TAC. Timepoint: At the beginning and at the end of the study. Method of measurement: kit.