Correlation of Venous Congestion and S Prime (S) in Echocardiography. Implications for Right Ventricular Function Assessment in Heart Failure Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- To investigate the correlation between venous congestion and S prime in Heart Failure patients.
研究概览
简要总结
Heart failure (HF) remains a major public health concern, affecting millions of individuals worldwide and contributing significantly to morbidity, mortality, and healthcare costs. Echocardiography is the cornerstone imaging modality for evaluating cardiac structure and function in HF patients.
VExUS serves as a valuable bedside tool for assessing venous congestion, utilizing measurements such as IVC diameter, hepatic vein Doppler, portal vein pulsatility, and renal vein Doppler to define venous congestion. Also it has been reported that bedside measurements can be used to assess tricuspid annular systolic velocity (S prime or S’) derived from Tissue Doppler Imaging(TDI).
Hence, we propose to study the efficacy of RV function by using S’ in predicting venous congestion in heart failure patients admitted to Cardiac Critical care Unit (CCU). Additionally, our aim is to investigate the relationship between the extent of venous congestion assessed using VExUS and S’.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Adult patients (aged above 18 years) diagnosed with heart failure according to established guidelines (AHA guidelines).
- •2.Patients undergoing echocardiography for clinical indications.
- •Ability to provide informed consent.
排除标准
- •1.Patients with contraindications to echocardiography.
- •2.Patient is on mechanical ventilator support with peep more than 5 and NIV of EPAP of more than 10 3.Patients with severe comorbidities including, but not limited to- a) End-stage renal disease requiring dialysis b) Advanced liver disease (examples – cirrhosis with significant portal hypertension and massive ascites) c) Advanced malignancy with limited life expectancy (less than 6 months) d) Decompensated severe chronic obstructive pulmonary disease (COPD) e) Pregnancy f) Active systemic infections requiring hospitalization or intravenous antibiotics g) Severe non-cardiac medical conditions requiring intensive medical management or surgery.
结局指标
主要结局
To investigate the correlation between venous congestion and S prime in Heart Failure patients.
时间窗: Baseline assessment
次要结局
- To assess the impact of venous congestion on RV systolic function and to evaluate the prognostic implications of reduced S prime in the presence of venous congestion.(Baseline assessment)
研究者
Dr Pramukh Hegde
Narayana Institute of Cardiac Sciences