Effect of probiotic yoghurt on level of blood glucose in obese and overweight pregnant wome
Phase 2
- Conditions
- impaired blood glucose.Abnormal glucose tolerance test
- Registration Number
- IRCT201604013706N31
- Lead Sponsor
- Research Deputy of Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 130
Inclusion Criteria
20-22 weeks of pregnancy; FBS<92 mg/dl; BMI=25; age= 18 years; able to read and write
Exclusion criteria: multiple pregnancy; prior history of GDM; taking any medication likely to influence metabolism of glucose (in particular metformin, glucocorticoids or immunosuppressants); medical condition associated with altered glucose metabolism (in particular Cushing's syndrom/disease and hepatic cirrhosis); known major fetal abnormality; known regular ingestion of other probiotics; smoking; antibiotic intake during current pregnancy
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Fasting blood glucose. Timepoint: Before the intervention, 4 weeks after intervention. Method of measurement: labratory assessment.;Blood glucose level 1 hour after intaking 75g oral glucose. Timepoint: 4 weeks after intervention. Method of measurement: labratory assessment.;Blood glucose level 2 hours after intaking 75g oral glucose. Timepoint: 4 weeks after intervention. Method of measurement: labratory assessment.
- Secondary Outcome Measures
Name Time Method Gestational diabetes. Timepoint: 4 weeks after intervention and after delivery. Method of measurement: Labratory Assessment.;Peeclampsia. Timepoint: 37th weeks of pregnancy and after delivery. Method of measurement: clinical (blood preassure) & labratory (proteinuria) assessment.;Preterm delivery. Timepoint: after delivery. Method of measurement: medical record assessment.;Birth weight. Timepoint: at birth, 10 days after birth. Method of measurement: medical record assessment, measurment of weight 10-12 days after birth by the researcher.;Macrosomia or Large for gestational age. Timepoint: after delivery. Method of measurement: based on birth weight.;Neonatal death. Timepoint: 30 days after birth. Method of measurement: asking from participant (woman) via calling.;Neonatal billirubine level. Timepoint: 3-5 days after delivery. Method of measurement: labratory assessment.