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Clinical Trials/NCT05268978
NCT05268978
Completed
N/A

SHAPES Advanced Telemonitoring of Patients With Heart Failure in Home Environment

University Hospital Olomouc1 site in 1 country25 target enrollmentNovember 11, 2022
ConditionsHeart Failure

Overview

Phase
N/A
Intervention
Not specified
Conditions
Heart Failure
Sponsor
University Hospital Olomouc
Enrollment
25
Locations
1
Primary Endpoint
Evaluation of the effect of step telemonitoring during uptitration of heart failure medication.
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Heart failure is currently not only a major medical but also a socio-economic problem. Its prevalence is estimated at 1-2% of the population with an exponential increase in older age groups. A very important part of the treatment of heart failure is the gradual uptitration of therapy to the maximum tolerated doses. Properly conducted therapy titration requires more frequent patient contact. Thanks to the introduction of telemedicine techniques, the investigators can communicate more effectively with the patient, reach the target doses of heart failure medication faster and subsequently reduce the number of hospitalizations due to worsening of heart failure.

This study investigates effect of advanced telemonitoring of patients with heart failure in home environment.

Registry
clinicaltrials.gov
Start Date
November 11, 2022
End Date
May 1, 2023
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
University Hospital Olomouc
Responsible Party
Principal Investigator
Principal Investigator

Ladislav Stanke

Principal Investigator

University Hospital Olomouc

Eligibility Criteria

Inclusion Criteria

  • LVEF ≤ 40%
  • exclusion of obstructive coronary artery disease
  • NTproBNP ≥ 125pg/ml
  • ≥ 60 years of age
  • Informed written and verbal consent
  • Able to participate in study activities

Exclusion Criteria

  • LVEF ≥ 40%
  • Ischaemic ethiology of cardiomyopathy
  • NTproBNP ≤ 125pg/ml
  • Severe psychological disturbances
  • Absence of collaboration (informed consent)
  • BP ≤ 110mmHg without hypertensive medication

Outcomes

Primary Outcomes

Evaluation of the effect of step telemonitoring during uptitration of heart failure medication.

Time Frame: 3 month

Uptitration of therapy guided by data from the medical and other devices (tablet with smartwatch providing data from the pedometer, i.e. number of steps) provided to the patients with heart failure in home environment.

Evaluation of the effect of ECG telemonitoring during uptitration of heart failure medication.

Time Frame: 3 month

Uptitration of therapy guided by data from medical and other devices (tablet with mobile ECG) provided to the patients with heart failure in home environment.

Evaluation of the effect of body water telemonitoring during uptitration of heart failure medication.

Time Frame: 3 month

Uptitration of therapy guided by data from medical and other devices (tablet and diagnostic weight scales for monitoring body water percentage) provided to the patients with heart failure in home environment.

Evaluation of the effect of blood pressure telemonitoring during uptitration of heart failure medication.

Time Frame: 3 month

Uptitration of therapy guided by data from medical and other devices (tablet and blood pressure monitor recording systolic and diastolic blood pressure) provided to the patients with heart failure in home environment.

Evaluation of changes in diastolic dysfunction by echocardiography at the beginning vs. at the end of study.

Time Frame: 3 month

Assessment of the effect of heart failure therapy (left ventricular reverse remodelation) by evaluation of changes in diastolic dysfunction.

Evaluation of the effect of body weight telemonitoring during uptitration of heart failure medication.

Time Frame: 3 month

Uptitration of therapy guided by data from medical and other devices (tablet and diagnostic weight scales for monitoring weight in kilograms) provided to the patients with heart failure in home environment.

Evaluation of changes of NTproBNP levels at the beginning vs. at the end of the study.

Time Frame: 3 month

Evaluation of changes of NTproBNPlevels as a marker of effective therapy of heart failure.

Evaluation of changes in LVEF echocardiographic parameter at the beginning vs. at the end of study.

Time Frame: 3 month

Assessment of the effect of heart failure therapy (left ventricular reverse remodelation) by evaluation of changes in LVEF echocardiographic parameter

Evaluation of changes in LVEDD echocardiographic parameter at the beginning vs. at the end of study.

Time Frame: 3 month

Assessment of the effect of heart failure therapy (left ventricular reverse remodelation) by evaluation of changes in LVEDD echocardiographic parameter

Evaluation of changes in LAVi echocardiographic parameter at the beginning vs. at the end of study.

Time Frame: 3 month

Assessment of the effect of heart failure therapy (left ventricular reverse remodelation) by evaluation of changes in LAVi echocardiographic parameter

Evaluation of the effect of blood oxygen saturation telemonitoring during uptitration of heart failure medication.

Time Frame: 3 month

Uptitration of therapy guided by data from medical and other devices (tablet and pulse oximetry device to monitor blood oxygen saturation in percents) provided to the patients with heart failure in home environment.

Evaluation of changes in LVESD echocardiographic parameter at the beginning vs. at the end of study.

Time Frame: 3 month

Assessment of the effect of heart failure therapy (left ventricular reverse remodelation) by evaluation of changes in LVESD echocardiographic parameter

Study Sites (1)

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