Living Donor Liver Transplant for Unresectable Colorectal Liver Metastases
- Conditions
- Colorectal Cancer Metastatic
- Registration Number
- NCT05248581
- Lead Sponsor
- University of Rochester
- Brief Summary
The goal of this study is to create a data registry to capture clinical, pathologic, and molecular data/outcomes for patients with metastatic colorectal cancer who undergo live donor liver transplantation.
- Detailed Description
The goal of this study is to create a data registry to capture clinical, pathologic, and molecular data/outcomes for patients with metastatic colorectal cancer who undergo live donor liver transplantation.
Our primary outcome of interest was the OS and recurrence-free survival (RFS) of patients who underwent LDLT at our center.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 25
- Age ≥ 18
- Non-amenable to curative hepatic resection as defined by FLR <30%
- Histologically confirmed adenocarcinoma of the colon or rectum
- Candidate for LDLT for colorectal liver metastasis per the University of Rochester liver transplant program
- Not a candidate of the LDLT liver transplant protocol for treatment of colorectal liver metastasis.
- Unwilling to consent
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method percentage overall survival 5 years OS proportions to be calculated at 1, 3, and 5 years with Kaplan Meier analysis
percentage of patients with recurrence free survival 5 years RFS proportions to be calculated at 1, 3, and 5 years with Kaplan Meier analysis
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of Rochester Medical Center
🇺🇸Rochester, New York, United States
University of Rochester Medical Center🇺🇸Rochester, New York, United StatesRoberto Hernandez-Alejandro, MDContactroberto_hernandez@urmc.rochester.edu