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Identification of Viral Variants Involved in the Transmission of Hepatitis C and Characterization of Antigenic and Functional Properties of Their Envelope Glycoproteins

Not Applicable
Completed
Conditions
Hepatitis C
Registration Number
NCT02574884
Lead Sponsor
University Hospital, Tours
Brief Summary

The study consists to Identify viral variants involved in the transmission of hepatitis C and characterize the antigenic and functional properties of their envelope glycoproteins at very early stage of infection (before seroconversion).

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
8
Inclusion Criteria
  • age > 18 years
  • agree to participate in this study (signing the consent form or information form signed and letter of no objection for subjects contaminated by blood exposure).

These criteria are specific to contaminated subjects:

  • primary infection before development of HCV antibody (seroconversion): nucleic acid testing positive in the absence of HCV antibodies.

These criteria are specific to individual sources :

  • HCV antibody positive.
Exclusion Criteria
  • refusal to participate
  • private about freedom
  • under guardianship
  • under justice
  • minor or major person unable to consent

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
HCV serological markersup to 30 months

Immunoblot analysis from blood samples collected during the study

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Chru de Tours

🇫🇷

Tours, France

Chru de Tours
🇫🇷Tours, France

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