Can coronary artery calcium (CAC) score be calculated on radiotherapy planning computed tomography (CT) scans? (RO-CARDIAC)

Not Applicable

Active, not recruiting

• Conditions: Cancer; Heart disease; Cancer - Any cancer; Cardiovascular - Coronary heart disease

• Registration Number: ACTRN12621001343897
• Lead Sponsor: GenesisCare

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-10-07
• Last Update Posted: 18 July 2023

Recruitment & Eligibility

• Status: Active, not recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Age 18 years or older
• Has provided written informed consent for participation
• Histological or cytologically confirmed malignancy
• Undergoing thoracic CT for radiotherapy planning
• Receiving radiotherapy, with curative intent, as part of standard treatment for malignancy
• Optional sub-study only: Resides in Western Australia

Exclusion Criteria

•Pregnancy or lactation
•Known coronary artery disease.
•Currently under the care of a cardiologist
•Life expectancy < 5 years
•Any other factor which, in the opinion of the study investigator, would adversely impact on the patient’s ability to participate in the study safely and fully.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Proportion of radiotherapy planning CT scans that coronary artery calcium score can be successfully calculated in patients being planned for radiotherapy for malignancy will be determined based on the number of CAC scores provided for participants by the central cardiologist.[At completion of recruitment];Proportion of patients with CAC score >0 determined by reviewing CAC scores received from the central cardiologist. [At completion of recruitment];Establishing a referral to pathway to CardioOncology clinic for assessment and management of high-risk patients. This will be measured by pre and post study surveys of clinicians (radiation oncologists and cardiologists) about CardioOncology referrals to assess the feasibility of the pathway. The surveys will be designed specifically for the study. [Surveys will be completed by clinicians prior to commencement of study recruitment and following end of study once all patients have completed follow-up.]