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临床试验/NCT04360291
NCT04360291Unknown不适用

Impact de la Restriction du Champ Visuel Sur l'Exploration Visuelle

Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts1 个研究点 分布在 1 个国家目标入组 45 人开始时间: 2019年11月4日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
45
试验地点
1
主要终点
Fixation strategy

研究概览

简要总结

To communicate with the observer and guide his gaze on the canvas, painters have developed different stylistic processes that artists, in the manner of scientists, have acquired on the functioning of human visual perception. This direct communication between the artist and the observer is strongly impacted for people with visual impairments.

In order to improve the accessibility and autonomy of visually impaired people in museums and to allow each observer to feel the visual and emotional experience closest to the original work of the artist, it is essential to identify the modifications. perceptive generated by the constriction of vision

详细描述

In this experiment, the investigators study the adaptive strategies developed by people with retinitis pigmentosa in the perception of figurative works of art. Peripheral vision is crucial for detecting objects and directing attention to the relevant areas of the environment, while central vision, of high spatial resolution, is especially essential for identifying the nature of objects. The integration of perceived information in peripheral vision and central vision makes it possible to quickly and effortlessly develop a spatial representation of the environment, to activate categorical knowledge on the observed scene and to relate the various objects perceived. However, with the progressive constriction of the visual field, the visual exploration of the subject RP can not be carried out with the strategies used by the healthy subjects, in which the targets of the saccades are in particular determined according to the information perceived in peripheral vision.

Through the recording of eye movements, the investigators compare the differences in visual explorations of people with retinitis pigmentosa and healthy people with or without a simulated deficit.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Prospective

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •no visual pathology
  • •Age ≥ 18 and <65 years
  • •Binocular visual acuity ≥8 / 10th or ≤ +0.10 logMAR
  • •Comprehension of the written and spoken French language
  • •Signed consent to participate in the study
  • •Health insurance affiliation
  • •Visit to an ophthalmologist less than a year old

排除标准

  • •Pregnant or lactating woman
  • •Ocular pathology that may interfere with planned assessments
  • •Treatment that may interfere with planned assessments
  • •Participation in another study that may interfere with this study.
  • •Severe pathology unbalanced or interfering with planned assessments.
  • •Neurological deficit including history of epileptic pathology, photosensitive epilepsy, sensory-motor coordination disorders, vestibular or cerebellar pathology
  • •Inability to give consent personally.
  • •Adults protected by law.
  • •Inclusion Criteria:
  • •Retinopathy pigmentary dystrophy rods-cones.
  • •Binocular visual acuity ≥4 / 10 (≤0.4 logMAR).
  • •Horizontal diameter of the residual Goldmann field of view ≤ 25 ° of binocular diameter at III
  • •Comprehension of the French language, written or oral.
  • •Signed consent
  • •Visual assessment less than 6 months old
  • •Exclusion Criteria:
  • •Pregnant or nursing woman.
  • •Ocular pathology that may interfere with planned assessments.
  • •Treatment that may interfere with planned assessments.
  • •Severe pathology unbalanced or interfering with planned assessments.
  • •Participation in another study that may interfere with this study.
  • •Neurological deficit including antecedent of epileptic pathology, photosensitive epilepsies, non-visual sensory disturbances, motor disorders, or sensorimotor coordination disorders, vestibular or cerebellar pathology.
  • •Inability to give consent personally.
  • •Adults protected by law.

结局指标

主要结局

Fixation strategy

时间窗: through study completion,, an average of 1 year

The fixation strategy characterized by the path of the gaze of the subjects on the screen to locate the targets.

Eye movements

时间窗: through study completion,, an average of 1 year

Eye movements will be recorded by an eye trackervisual impairment whose peripheral visual field is masked They will be invited to observe scenes of human interaction presented on photographs, pictorial works or artificial scenes with or without prior instruction. In addition to the elementary variables recorded during the exploration by these subjects, such as the number, the amplitude or the orientation of the saccades, the sequence of fixations will be analyzed to define the exploratory strategy used.

Target location accuracy

时间窗: through study completion,, an average of 1 year

Target location accuracy, defined by the distance between the point of re-fixation on the target and the actual position of the target

次要结局

未报告次要终点

研究者

发起方
Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
申办方类型
Other
责任方
Sponsor

研究点 (1)

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