Effect of standard treatment for Iron deficiency anemia over effects of fortified dark chocolate with iron and folic acid among school children
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 176
- 试验地点
- 1
- 主要终点
- The efficacy of fortified dark chocolate for increasing the level of haemoglobin and anemia status
研究概览
简要总结
Iron deficiency (ID), the primary cause of anemia, has adverse effects on both human health and socioeconomic development, with increased susceptibility to infections, elevated risk of maternal and child mortality, impaired cognitive and physical development of children, and lower work productivity of adults .The 2011 estimates suggest anemia affects around 800 million children and women worldwide. Anemia is primarily caused by iron deficiency but also by other micronutrient deficiencies such as vitamins B2, folate, and B12.
Iron deficiency during the school years can impair physical and mental development and reduce school attendance by increasing morbidity. Some studies reported that it is still possible to improve cognition at school age by improving iron status , as well as positive effects on morbidity and growth, but the overall effects on these outcomes were equivocal and more evidence is required from studies in different contexts.
Food fortification is an effective and cost effective, medium-term approach to improve micronutrient status and is sustainable once established. Since the prevalence of micronutrient deficiencies are generally higher and the consequences are graver in children, the identification of a child friendly vehicle is important.
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- None
入排标准
- 年龄范围
- 12.00 Year(s) 至 17.00 Year(s)(—)
- 性别
- All
入选标准
- •â Age- 12 to 17 years school children 2)â Children with mild to moderate anaemia.
排除标准
- •Blood haemoglobin less than 8g/dl.
- •Patient having occult blood positive on stool examination.
- •Any other type of anemia except Iron Deficiency Anemia (IDA).
- •IDA with any associated severe complication.
结局指标
主要结局
The efficacy of fortified dark chocolate for increasing the level of haemoglobin and anemia status
时间窗: Baseline/3months
次要结局
- The efficacy of fortified dark chocolate for improving anaemia status and to improve micronutrient status(Baseline/3months)
研究者
Dr Indhumathi RK
Saveetha Medical College and Hospital
