JPRN-jRCTs051180039已完成1 期
Preoperative chemoradiotherapy using intensity-modulated radiotherapy for locally advanced rectal cancer: single institutional pilot study - Preoperative CRT using IMRT for LARC
Mizowaki Takashi0 个研究点目标入组 12 人开始时间: 2019年1月30日最近更新:
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 12
研究概览
简要总结
Preoperative chemoradiotherapy using IMRT for this population might alleviate acute gastrointestinal toxicity, achieving high LRC and sphincter preservation.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 <= 80age old（—）
- 性别
- All
入选标准
- •1) Histologically confirmed adenocarcionma
- •2) Resectable rectal cancer
- •i) clinically T3-4 and N0-2
- •ii) Ra or Rb
- •iii) Inferior margin of tumor is located below the peritoneal reflection
- •3) No hepatic, peritoneal metastasis
- •4) 20-80 years
- •5) Performance Status: 0-2
- •6) No previous treatment
- •7) Adequate organ function
- •8) Able to take drugs orally
- •9) Written informed consent
排除标准
- •1) Active other synchronous cancer
- •2) Receiving flucytosin or atazonavi
- •3) Suffering the active infection
- •4) Uncontrollable comorbidity
- •5) Pregnant or breastfeeding women,
- •6) Reciving steroid medication
- •7) Difficult to join due to mental disorder
研究者
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