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Clinical Trials/NCT07322276
NCT07322276
Recruiting
Not Applicable

Effects of Exercise Timing and Physical Activity Level on Sleep Quality and Body Temperature

Centre Hospitalier Universitaire de Saint Etienne1 site in 1 country42 target enrollmentStarted: January 23, 2026Last updated:
InterventionsAerobic Exercise

Overview

Phase
Not Applicable
Status
Recruiting
Enrollment
42
Locations
1
Primary Endpoint
Duration of deep slow-wave sleep

Overview

Brief Summary

Modern lifestyles are marked by a prevalence of sedentary behaviors and physical inactivity, which have been linked to numerous adverse health effects. While regular physical exercise is a well-established countermeasure, exercising in the late afternoon may paradoxically disrupt deep sleep due to increased core body temperature. Inactive and sedentary individuals, who often have impaired autonomic function compared to endurance-trained athletes, may be particularly susceptible to these negative effects, potentially resulting in compromised thermoregulation and exacerbated disruptions to deep sleep, a critical stage of sleep essential for overall recovery. Therefore, this study aims to investigate the impact of aerobic exercise performed in the late afternoon versus morning on: 1) deep sleep and sleep onset latency; and 2) core body temperature and its autonomic regulatory mechanisms on endurance-trained and inactive-sedentary people.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Crossover
Primary Purpose
Basic Science
Masking
None

Eligibility Criteria

Ages
18 Years to 30 Years (Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Group "Inactive" :No regular exercise practice (inactive people that don't follow the WHO recommendations) and have sedentary behaviors
  • Group "Active": Regular exercise (athletes that are specialized in aerobic exercise, with more than 300 minutes per-week over 6 months and practice at regional level).

Exclusion Criteria

  • Have sleep disorders medically diagnosed or detected by sleep forms cutoffs (clinical insomnia by ISI, severe risk of obstructive sleep apnea by Stop-Bang, bad sleep quality by PSQI.
  • Have a diagnosed mental health condition requiring treatment
  • Have renal, respiratory, cardiovascular or neuromuscular disease medically diagnosed.
  • Be pregnant or breastfeeding

Arms & Interventions

"Inactive-sedentary" group

Active Comparator

inactive participants that realize 3 experimental conditions: evening exercise, morning exercise and control (no-exercise).

Intervention: Aerobic Exercise (Other)

"Active" group

Experimental

endurance athletes that realize 3 experimental conditions: evening exercise, morning exercise and control (no-exercise).

Intervention: Aerobic Exercise (Other)

Outcomes

Primary Outcomes

Duration of deep slow-wave sleep

Time Frame: Once weekly for three weeks (day 1, day 7, day 14, day 21)

Evaluation of the duration of deep slow-wave sleep (N3 stage) quantified by the EEG signal from polysomnography (Nox A1, Resmed®, USA).

Secondary Outcomes

  • Assessment of core temperature(Once weekly for three weeks (Day 1, Day 7, Day 14, Day 21))
  • Evaluation of autonomic nervous system thermoregulation(Once weekly for three weeks (Day 1, Day 7, Day 14, Day 21))
  • Complementary sleep evaluation(Once weekly for three weeks (Day 1, Day 7, Day 14, Day 21))

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (1)

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