Effect of prophylactically administered ketorolac and diclofenac potassium on the efficacy of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis.
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 130
研究概览
简要总结
This study showed favourable results with prophylactic use of ketorolac and diclofenac potassium drugs on the efficacy of anesthesia, which was ascertained as no or mild pain peri-operatively after taking the drug. Among the total sample size, effective IANB anesthesia block was achieved in 70 (53.8%) participants, while IANB block remained ineffective in 60 (46.2%) participants. The number of successful IANB in ketorolac group was 42 (64.6%) and unsuccessful blocks were 23 (35.4%), while in diclofenac group, 28 (43.1%) participants had effective blocks as compared to 37 (56.9%) unsuccessful anesthesia. The higher number of successful IANB in ketorolac group (64.6%) as compared to diclofenac group (43.1%) shows better results were obtained with prophylactic use of ketorolac drug.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 60 Years（—）
- 性别
- All
入选标准
- •Healthy adult patients
- •Age 18 - 60 years
- •First and second mandibular molars with history of Symptomatic Irreversible Pulpitis
- •Moderate or severe pain score on Visual Analogue Scale
- •No premedication with any drug 12 hours prior to treatment
排除标准
- •Any known allergy to NSAID medication or lignocaine
- •Pregnant females
- •Lactating females
- •Those who will not be able to give informed consent
- •Patients with active peptic ulcers
- •Teeth declared necrotic upon investigation with cold test using ethyl chloride
- •Patients only experiencing mild pain (0-3) on Visual Analogue Scale