The Effect of Age and Dietary Protein Intake on Myocellular Characteristics Following a Single Bout of Resistance Exercise in Healthy Men
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 34
- 试验地点
- 1
- 主要终点
- Muscle fiber myonuclear and stem cell content
研究概览
简要总结
In the present study, the effects of age and dietary intake will be assessed on myocellular characteristics during 72 hours after a resistance type exercise session.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 85 Years(Adult, Older Adult)
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •healthy men between the ages of 18-30 or 70-85 years
排除标准
- •Subjects with a recent history or current state of cardiovascular disease, COPD, Parkinson, rheumatoid arthritis, musculoskeletal/orthopaedic disorders, renal disorder, cognitive impairment.
研究组 & 干预措施
Young regular diet
During the time of the study this group will adhere to a standardized regular diet.
干预措施: Adhere to a specific standardized diet for 4 days (Behavioral)
Young low protein diet
During the time of the study this group will adhere to a standardized low protein diet.
干预措施: Adhere to a specific standardized diet for 4 days (Behavioral)
Young high protein
During the time of the study this group will adhere to a standardized high protein diet.
干预措施: Adhere to a specific standardized diet for 4 days (Behavioral)
Elderly
During the time of the study this group will adhere to a standardized high protein diet
干预措施: Adhere to a specific standardized diet for 4 days (Behavioral)
结局指标
主要结局
Muscle fiber myonuclear and stem cell content
时间窗: 72 hours after a single bout resistance type exercise
Muscle fiber myonuclear and stem cell content
时间窗: baseline
Muscle fiber myonuclear and stem cell content
时间窗: 12 hours after a single bout of resistance type exercise
Muscle fiber myonuclear and stem cell content
时间窗: 24 hours after a single bout of resistance type exercise
Muscle fiber myonuclear and stem cell content
时间窗: 48 hours after a single bout of resistance type exercise
次要结局
未报告次要终点
研究者
Lex Verdijk
Dr.
Maastricht University Medical Center
