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临床试验/NCT01220037
NCT01220037已完成不适用

The Effect of Age and Dietary Protein Intake on Myocellular Characteristics Following a Single Bout of Resistance Exercise in Healthy Men

Maastricht University Medical Center1 个研究点 分布在 1 个国家目标入组 34 人开始时间: 2010年4月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
34
试验地点
1
主要终点
Muscle fiber myonuclear and stem cell content

研究概览

简要总结

In the present study, the effects of age and dietary intake will be assessed on myocellular characteristics during 72 hours after a resistance type exercise session.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Double (Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 85 Years(Adult, Older Adult)
性别
Male
接受健康志愿者
是

入选标准

  • •healthy men between the ages of 18-30 or 70-85 years

排除标准

  • •Subjects with a recent history or current state of cardiovascular disease, COPD, Parkinson, rheumatoid arthritis, musculoskeletal/orthopaedic disorders, renal disorder, cognitive impairment.

研究组 & 干预措施

Young regular diet

Experimental

During the time of the study this group will adhere to a standardized regular diet.

干预措施: Adhere to a specific standardized diet for 4 days (Behavioral)

Young low protein diet

Experimental

During the time of the study this group will adhere to a standardized low protein diet.

干预措施: Adhere to a specific standardized diet for 4 days (Behavioral)

Young high protein

Experimental

During the time of the study this group will adhere to a standardized high protein diet.

干预措施: Adhere to a specific standardized diet for 4 days (Behavioral)

Elderly

Experimental

During the time of the study this group will adhere to a standardized high protein diet

干预措施: Adhere to a specific standardized diet for 4 days (Behavioral)

结局指标

主要结局

Muscle fiber myonuclear and stem cell content

时间窗: 72 hours after a single bout resistance type exercise

Muscle fiber myonuclear and stem cell content

时间窗: baseline

Muscle fiber myonuclear and stem cell content

时间窗: 12 hours after a single bout of resistance type exercise

Muscle fiber myonuclear and stem cell content

时间窗: 24 hours after a single bout of resistance type exercise

Muscle fiber myonuclear and stem cell content

时间窗: 48 hours after a single bout of resistance type exercise

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Lex Verdijk

Dr.

Maastricht University Medical Center

研究点 (1)

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