Clinical and Radiographic Evaluation of Open Flap Debridement With or Without Nanocrystalline Hydroxyapatite Bone Graft in Management of Periodontal Intrabony Defects
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- change in probing pocket depth
研究概览
简要总结
The present clinical trial included 20 patients (11 females and 9 males, aged 36 to 56 years) suffering from moderate or advanced chronic periodontitis. Subjects were recruited from the outpatient clinic, Department of Oral Medicine and Periodontology, Faculty of Dentistry, Cairo University. This clinical trial was meant to assess clinically and radiographically the possible predictable results regarding the use of nanocrystalline hydroxyapatite bone graft substitute together with open flap debridement versus open flap debridement alone in the treatment of periodontal intrabony defects.
详细描述
periodontal intrabony defects in patients with moderate or advanced chronic periodontitis were treated with open flap debridement only in the control group while open flap debridement and Nanocrystalline Hydroxyapatite bone graft substitute was performed for the intervention group. probing pocket depth, clinical attachment level, gingival index, plaque index, gingival recession and bone defect area were assessed at baseline and six months post surgically to evaluate the possible improvement in the clinical and radiographic outcomes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 35 Years 至 56 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •systemically healthy patients
- •diagnosed with moderate to advanced chronic periodontitis
- •periodontal defects with at least one site with probing pocket depth (PPD) ≥ 5mm, clinical attachment loss (CAL) ≥ 4mm and two or three-walled intra-bony defects ≥ 3mm
- •evidence of intrabony defects using periapical radiographs
排除标准
- •teeth with suprabony defects or 1-wall intrabony defects
- •pregnant or lactating women
- •patients taking any medication 3 months prior to the study
- •patients receiving any periodontal treatment 6 months prior to study initiation
- •former or current smokers.
结局指标
主要结局
change in probing pocket depth
时间窗: baseline and after six months
William's graduated periodontal probe used to measure probing pocket depth from the gingival margin to the base of the sulcus
次要结局
- change in clinical attachment level(baseline and after six months)
- change in the bone defect area(baseline and after six months)
研究者
Weam Ahmed Elbattawy
Lecturer
Cairo University