NL-OMON56173
Recruiting
Not Applicable
Standard versus Pre-emptive Antibiotic Treatment to Reduce the Rate of Infectious Outcomes after Whipple procedure (SPARROW): a multicenter, randomized controlled trial - SPARROW trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Pancreatic cancer
- Sponsor
- eids Universitair Medisch Centrum
- Enrollment
- 344
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients undergoing elective pancreatoduodenectomy with a high risk for
- •contaminated bile defined as patients with preoperative biliary drainage or an
- •ampullary malignancy.
- •Age of 18 years
Exclusion Criteria
- •Pregnancy
- •Contraindication for the study antibiotics (e.g. allergy or intolerance)
- •Indication for endocarditis prophylaxis
- •Preoperative planned therapeutic antibiotic treatment after surgery (i.e. for
- •cholangitis or liver abscesses)
- •A reduced renal function, defined as an eGFR of \<60 ml/min/1\.73m2 measured on
- •the closest timepoint prior to pancreatoduodenectomy
Outcomes
Primary Outcomes
Not specified
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