Salivary Melatonin Levels and Sleep Quality in Patients With Burning Mouth Syndrome
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 45
- 试验地点
- 1
- 主要终点
- determining the level of salivary melatonin
研究概览
简要总结
Burning mouth syndrome is an idiopathic condition characterized by symptoms burning and / or pain of the oral mucosa with an orderly clinical finding. So far not found a unique way of treatment. It is a diagnosis that impairs the quality of life of patients, and consequently it can affect the quality of sleep. Melatonin is a hormone secreted from pineal gland and regulates the day-night rhythm of man, and whose production in the body decreases aging. The level of melatonin in saliva correlates well with the level of melatonin in plasma, therefore they are advantages of determining from saliva painlessness and non-invasiveness of the procedure itself. The purpose of this study was to compare the level of melatonin in saliva and the quality of sleep with help of the Epworth Sleepiness Scale in patients with burning mouth syndrome and control groups of patients without subjective oral disorders and with an orderly clinical finding.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 65 Years(Adult, Older Adult)
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •female patients
- •primary burning mouth syndrome
- •without oral lesions
排除标准
- •secondary burning mouth syndrome
- •male gender
- •patients with oral lesions
结局指标
主要结局
determining the level of salivary melatonin
时间窗: January 2021-July 2021
The level of salivary melatonin will be determined in frozen samples of unstimulated saliva samples
次要结局
- determining the difference in Epworth's sleepiness scale(January 2021-July 2021)
研究者
Božana Lončar Brzak
Assistant Professor at the Department of Oral Medicine
University of Zagreb
