The Effect of Fluids Flushed in Pediatric Cardiac Catheterization Procedures on Lung Ultrasound Score: A Prospective Observational Study
试验速览
- 阶段
- 不适用
- 入组人数
- 43
- 试验地点
- 1
- 主要终点
- Change between lung ultrasound score before and after fluids flushed
研究概览
简要总结
Therapeutic catheterizations substituted many traditional surgical procedures with the advance of transcatheter techniques.
Pediatric patients are more liable to fluid overload due to their smaller weights compared to adults and the risk increases in pediatrics with congenital heart diseases due to lower tolerability and reserve capacity and some of them may already have a degree of heart failure. Fluid overload increases the incidence of morbidity and mortality in such patients.
The aim of our study is to observe the amount of fluids needed for flushing during pediatric cardiac catheterization (in ml/kg) and asses its effect on total lung water and PaO2/FiO2, aiming to develop a useful protocol for the amount of fluids used.
详细描述
.Objectives: The objective of this study is to assess lung water by comparing the calculated values of lung score by ultrasound, PaO2/FiO2 ratio and PaCO2 obtained from arterial blood gases' samples before and after the procedures.
. Study Design:
- A prospective observational study. Study Method
- Population of study & disease condition Children from 1 month to 6 years undergoing cardiac catheterization procedures..
- Study setting:
This study will be conducted at Abo El Reesh Paediatric Hospital, Faculty of Medicine, Cairo University.
- Methodology in details: General anesthesia After interviewing and taking proper history from the parents, examining the patients, checking all routine investigations, informed consent will be taken after discussion with them.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Month 至 6 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Pediatric patients undergoing diagnostic cardiac catheterization procedures.
排除标准
- •Age <1 month and >6 years.
- •Preoperative mechanical ventilation.
- •Heart failure
- •Patients with oligemic lung diseases.
结局指标
主要结局
Change between lung ultrasound score before and after fluids flushed
时间窗: at the start of the procedure of cardiac catherization and immediately after the end of the procedure
heparinized fluids are flushed throughout catheterization through venous and arterial sheathes , ultrasound score will be measured before and after the flushing
次要结局
- Correlation between lung score and PaO2/FiO2 ratio(immediately before and immediately after the procedure.)
- . Change between PaO2/FiO2 ratio(immediately before and immediately after the procedure.)
研究者
Mai Madkour
Associate professor
Cairo University