A Randomized, Double-blind, Placebo-controlled, Single Center Study of the Safety, Tolerability, Pharmacokinetics (Including Food Effects) of Single or Multiple Doses of ABT-639 in Healthy Adults and Elderly Subjects
Completed
- Conditions
- Zenuwpijn armen en benenNerve Pain
- Registration Number
- NL-OMON34223
- Lead Sponsor
- Abbott
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 124
Inclusion Criteria
18 - 55 years (Parts I, II and III), at least 65 years or older (Part IV), BMI 18 - 30kg/m2, no smoking for at least 6 months, good general health.
Exclusion Criteria
Suffering from: hepatitis B, cancer or HIV/AIDS. In case of participation in another drug study within 90 days before the start of this study or being a blood donor within 90 days from the start of the study. In case of donating more than 1.5 liters of blood in the 10 months prior the start of this study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Pharmacokinetics: plasma and urine ABT-639 concentrations, pharmacokinetic<br /><br>parameters<br /><br>Safety : adverse events, vital signs, ECG-parameters, laboratory parameters,<br /><br>physical examination, </p><br>
- Secondary Outcome Measures
Name Time Method <p>n.a.</p><br>