Evaluation of gastroesophageal reflux using high-resolution manometry and pH monitor after proximal gastrectomy
- Conditions
- gastric cancer
- Registration Number
- JPRN-UMIN000040514
- Lead Sponsor
- The University of Tokyo
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
Not provided
1) Patients within 1 year after proximal gastrectomy (except preoperative patients) 2) Patients who are expected to be difficult to complete the examination 3) Patients who can not suspend anti-acid drugs. 4) Patients who have already joined this trial 5) Patients with contraindication for esophagogastroduodenoscopy. a) hemodynamic and respiratory instability b) hemorrhagic (except anti-coagulant drugs) c) severe anastomotic stenosis d) stenosis or obstruction of the bowel distal to the duodenum e) intolerant to esophagogastroduodenoscopy 6) Patients who have difficulty in swallowing with the catheter inserted 7) Patients with allergy to the drugs we plan to use 8) Patients who are pregnant 9) Patients whom researchers regard as invalid
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The difference of internal pressure at the anastomotic site between the types of reconstructions at more than 1 year after proximal gastrectomy.
- Secondary Outcome Measures
Name Time Method The difference of DeMeester score between the types of reconstructions at more than 1 year after surgery. The change of internal pressure and DeMeester score before and after proximal gastrectomy. The associations between internal pressure or DeMeester score and quality of life. The associations between internal pressure or DeMeester score and body weight change or prognostic nutritional index.