NCT04215913尚未招募不适用
Integrative Analysis of Pulmonary Sarcomatoid Carcinoma (PSC)
Shanghai 10th People's Hospital1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2019年12月30日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- 10 years overall survival
研究概览
简要总结
Integrative Analysis of pulmonary sarcomatoid carcinoma (PSC)
详细描述
The investigators will analyzed proteomes of paired normal lung tissues and pulmonary sarcomatoid carcinoma with or without metastasis, sequenced transcriptomes, perform whole exome sequencing, and single nucleotide polymorphism (SNP) array profiling for triplets, each comprising normal lung tissue, primary pulmonary sarcomatoid carcinoma, and its synchronous matched metastasis, as well as analyzed genomics of lung cancer characterized previously by The Cancer Genome Atlas (TCGA) to conduct integrated proteogenomic analyses.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≤ 70 years with histologically proven LCLC
- •No severe major organ dysfunction
- •World Health Organization (WHO) performance status of 0 or 1
- •No prior cancer chemotherapy
排除标准
- •Severe major organ dysfunction
- •WHO performance status of >1
- •Prior cancer chemotherapy
结局指标
主要结局
10 years overall survival
时间窗: 10 years overall survival
10 years overall survival
次要结局
- 10 years disease-free survival(10 years disease-free survival)
研究者
Da Fu
Professor
Shanghai 10th People's Hospital
研究点 (1)
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