Respiratory Emissions in Healthy Participants
Not Applicable
Completed
- Conditions
- Healthy
- Interventions
- Behavioral: Exertional respiratory activities
- Registration Number
- NCT05169723
- Lead Sponsor
- Fisher and Paykel Healthcare
- Brief Summary
This is an randomised cross over trial in healthy participants measuring respiratory emissions during different respiratory activities.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
- Adults, over the age of 18 and able to give informed consent
- Symptom free from any respiratory illness in the last 48 hours
Exclusion Criteria
- Pregnant (where the participant feels that their pregnancy will make participation uncomfortable)
- Inability to give consent
- Current respiratory disease. Participants with well controlled asthma will be included (defined as asthma that the participant self-rates their asthma as being under control and that does not limit exercise, work)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Respiratory Activity 3 Exertional respiratory activities - Respiratory Activity 4 Exertional respiratory activities - Respiratory Activity 2 Exertional respiratory activities - Respiratory Activity 1 Exertional respiratory activities - Respiratory Activity 5 Exertional respiratory activities -
- Primary Outcome Measures
Name Time Method Count of total number of respiratory particles emitted during respiratory activities in the range of 0.3 to 25 microns Emission of particles will be collected and analysed for 2 minutes during each experimental condition Particles emitted will be counted using two different optical particle counters
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular pathways are influenced by exertional respiratory activities in healthy individuals' exhaled breath analysis?
How do different exertional respiratory maneuvers impact ventilation-perfusion mismatch biomarkers in NCT05169723?
Which volatile organic compound (VOC) profiles correlate with exertional respiratory activity outcomes in healthy participants?
What adverse events are reported during high-intensity exertional protocols in Fisher and Paykel Healthcare's respiratory trials?
How does NCT05169723 compare to non-invasive respiratory monitoring technologies like spirometry or capnography in healthy populations?
Trial Locations
- Locations (1)
Fisher and Paykel Healthcare
🇳🇿Auckland, New Zealand