ISRCTN83971151
已完成
3 期
An international randomized trial of additional treatments for COVID-19 in hospitalized patients who are all receiving the local standard of care
概览
- 阶段
- 3 期
- 干预措施
- 未指定
- 疾病 / 适应症
- COVID-19 (SARS-CoV-2 infection)
- 发起方
- World Health Organization
- 入组人数
- 11266
- 状态
- 已完成
- 最后更新
- 3年前
概览
简要总结
2020 Interim results article in https://doi.org/10.1101/2020.10.15.20209817 interim results in preprint (added 19/10/2020) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/33264556/ interim results for remdesivir, hydroxychloroquine, lopinavir and interferon (added 25/03/2021) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35512728/ final results and updated meta-analyses (added 06/05/2022)
研究者
入排标准
入选标准
- •1\. Adults (aged \=18 years) hospitalized with definite COVID\-19
- •2\. Not already receiving any of the study drugs
- •3\. Without known allergy or contraindications to any of them (in the view of the physician responsible for their care)
- •4\. Without anticipated transfer within 72 h to a non\-study hospital
- •Patients invited to join the study will be those who are admitted to a collaborating hospital; no wider recruitment efforts are expected
排除标准
- •Current exclusion criteria as of 21/04/2020:
- •1\. Any of the available study drugs are contra\-indicated (e.g. because of patient characteristics, chronic liver or heart disease, or some concurrent medication)
- •2\. Declined to participate in the study
- •Previous exclusion criteria:
- •1\. Any of the available study drugs are contra\-indicated (e.g. because of patient characteristics, chronic liver or heart disease, or some concurrent medication)
- •2\. Pregnant
- •3\. Declined to participate in the study
结局指标
主要结局
未指定
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