Study on the Relationship Between Periodontitis and Renal Disease
- Conditions
- Periodontitis
- Registration Number
- NCT02417363
- Lead Sponsor
- Zhejiang University
- Brief Summary
Analysis of inflammatory markers in periodontitis and patients with early and middle stage renal disease.
- Detailed Description
A total of 200 population is recruited, individuals are divided into four groups according to a periodontal examination and a general physical examination: healthy individuals ,periodontitis, renal disease patients with healthy periodontium, and renal disease patients wth peridontitis. Fasting blood samples and gingival crevicular fluid are collected from all individuals, and inflammatory markers are analysed for the four groups.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
- all participants were in general good health(except renal disease) and non-smoking
Exclusion Criteria
- less than 20 teeth in the dentin
- hypertension
- the presence of systemic disease (e.g., diabetes mellitus ,coronary heart disease, liver, or lung disease)
- a history or the symptom of any other acute or chronic infections
- systemic antibiotic treatment within previous 4 weeks
- periodontal treatment within1 month
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Inflammatory markers analysis of the four groups 3 months after sampling Analysis of inflammatory biomarkers of blood and gingival crevicular fluid samples of the four groups
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Affiliated Hospital of Stomatology, School of Medicine, Zhejiang University
🇨🇳Hangzhou, Zhejiang, China