Long-term Results of Rehabilitation of Patients With Myocardial Infarction After Endovascular Intervention on Coronary Arteries at the Outpatient Stage. Register
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 1,046
- 主要终点
- Combined
研究概览
简要总结
Endovascular intervention is one of the most effective treatment for acute coronary syndrome. Therefore, studying the impact of various medical rehabilitation programs on the course of coronary heart disease, patient quality of life, restenosis, and prognosis is of scientific and practical interest. Medical rehabilitation is a crucial stage in patient care after myocardial revascularization. Regular moderate-intensity physical activity helps improve endothelial function and has anti-inflammatory and antithrombogenic effects. Improving a patient's prognosis after myocardial infarction depends on the duration and intensity of cardiac rehabilitation programs, as well as the patient's motivation. Therefore, this issue requires further study, particularly in patients who have undergone endovascular interventions on coronary arteries.
详细描述
The study was an interventional (clinical) trial, randomized in parallel groups. A total of 1,046 patients were included.
A total of 1,046 patients of both sexes were randomized into two groups. Group 1 (control) patients received standard therapy required for patients undergoing coronary artery stenting during the acute phase of myocardial infarction. They continued their usual physical activity and attended a school for patients with myocardial infarction. Group 2 patients received standard therapy required for patients undergoing coronary artery stenting during the acute phase of myocardial infarction, attended a school for patients with myocardial infarction, and participated in a physical training program. The training program lasted over four months. Postoperatively, patients underwent blood tests, echocardiography, ECG, and bicycle ergometry. The next visit was performed after an average of eight years (with a maximum follow-up period of 11 years). Cardiovascular events were assessed at this stage. Patients who were unable to attend the clinic were interviewed by telephone.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Acute myocardial infarction, coronary artery stenting
排除标准
- •Age (younger 18 years, older 75 years)
研究组 & 干预措施
Physical training
Integrated Rehabilitation consisting of exercise training and school for patients
干预措施: Physical training program (Other)
Control
Standard follow-up and attending school for patients at the participating heart center
结局指标
主要结局
Combined
时间窗: 20 years
Cardiovascular mortality, non-fatal acute myocardial infarction, non-fatal stroke, need for revascularization
次要结局
- cardiovascular mortality(20 years)
- myocardial infarction(20 years)
- All-cause mortality(20 years)
- stroke(20 years)
- need for revascularization(20 years)
- Composite endpoint of major adverse cardiovascular events (MACE)(20 years)
- hospitalization due to cardiovascular complications(20 years)