Comparison of Predictive Factors Related to Coronary Artery Disease

Not Applicable

Completed

• Conditions: Coronary Artery Disease
• Interventions: Other: lifestyle modified project

• Registration Number: NCT01136343
• Lead Sponsor: Taipei Medical University WanFang Hospital

Brief Summary

In Taiwan, heart disease and cerebrovascular disease ranked the second and third of ten leading causes of death in female in 2007; half of these deaths is due to coronary artery disease (CAD). Postmenopausal status is an independent risk factor for CAD. Early assessment and proper management of risk factors may reduce the prevalence rate of CAD. In the past decade, despite increased attention to CAD in women, most studies focused on certain menopausal status instead of all phases of menopause or on risk factors limited to related metabolic syndrome. Because the prevalence of risk factors related to CAD is influenced by various physiological and lifestyle status in different menopausal statuses, the purpose of this study, at the first stage, is to explore respectively the risk factors of CAD among middle-aged women in three menopausal statuses. At the second stage, the influence of a lifestyle management program on risk factors modification among pre-menopausal women is examined in this study.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-02
• Study First Submitted: 2010-05-31
• Study First Submitted QC: 2010-05-31
• Study First Posted: 2010-06-03
• Primary Completion: 2012-08
• Study Completion: 2012-08
• Status Verified: 2023-03
• Last Update Submitted: 2023-03-19
• Last Update Posted: 2023-03-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 130

Inclusion Criteria

• diagnosis of CAD by coroangiography
• LVEF >30%

Exclusion Criteria

• impairment of physical activity
• history of psychiatric disorder, vital arrhythmia

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
lifestyle modified project	lifestyle modified project	education, counseling

Primary Outcome Measures

Name	Time	Method
lifestyle		physical activity, dietary, depression, anxiety

Secondary Outcome Measures

Name	Time	Method
biomarkers		hsCRP, homocysteine, leptin
metabolic	6 months	blood pressure, lipid profile, blood sugar, obesity

Trial Locations

Locations (1)

Wan Fang Hospital; 🇨🇳 Taipei, Taiwan