Study of Arterial Recanalization of the Central Retinal Artery Occlusions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- Dynamic retinal angiography data at 24 hours (+/- 24 hours)
Study Overview
Brief Summary
Central retinal artery occlusions (CRAO) are the equivalent of an ischemic stroke (IS) at the retinal level. They share the same risk factors and common pathology. Their incidence is lower (8.5 / 100,000) and the functional prognosis is unfavorable in 80% of cases with visual acuity (VA) <1/10. The diagnosis of an CRAO is clinically based on the sudden occurrence of a decrease in deep visual acuity with fundamentally signs of reactive ischemia. There is no data on early retinal arterial recanalization after CRAO, nor on the relationship between early recanalization (spontaneous or post-thrombolysis) and visual prognosis.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Central Retinal Artery Occlusion ≤ 24 hours
Exclusion Criteria
- •Retinal Dynamic angiography not performed within 48 hours of onset of symptoms
- •Occlusion of a branch of the central retinal artery
Outcomes
Primary Outcomes
Dynamic retinal angiography data at 24 hours (+/- 24 hours)
Time Frame: 24 hours (+/- 24 hours) following the beginning of symptoms
Proportion of patients with early arterial recanalization.The recanalization rate will be compared between thrombolysed patients and non-thrombolysed patients
Secondary Outcomes
No secondary outcomes reported