A Randomized Controlled Trial on Effect of Tai Chi versus aerobic exercise on Blood Pressure in Prehypertension Patients
- Conditions
- Prehypertension
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
1. Aged 18 to 65 years;
2. With a systolic blood pressure in the range of 120 mm Hg to 139 mm Hg and/or a diastolic blood pressure in the range of 80 mm Hg to 89 mm Hg;
3. No western medicine or traditional Chinese medicine, acupuncture and moxibustion were used to control blood pressure (or the treatment was discontinued for 2 weeks);
4. Willing to be randomized to Tai Chi group or aerobic exercise group;
5. Ability to complete written questionnaires and operate electronic equipment independently;
6. Able to give informed consent.
1. Secondary hypertension;
2. Pregnant and lactating women;
3. Non-dominant arm circumference > 50 cm;
4. Body mass index larger than 40.0 kg/m2;
5. Take benzodiazepines, antipsychotics or oral glucocorticoids (allowed to taken fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram and escitalopram stably within 3 months);
6. Diagnosed with diabetes mellitus and coronary heart disease;
7. Chronic kidney disease with eGFR < 60 mL/min;
8. With known autonomic neuropathy (such as Shy-Drager syndrome, orthostatic hypotension, white coat hypertension);
9. Male's alcohol intake was more than 25 g/day or 140 g/week or female's alcohol intake was more than 15 g/day or 80 g/week;
10. Has played Tai Chi more than once a month in the past six months;
11. Vigorous sports activities more than three times a week;
12. Severe musculoskeletal problems lead to the inability to practise Tai Chi;
13. Current participants in clinical trials of other drugs or external therapies.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method systolic blood pressure in office blood pressure;
- Secondary Outcome Measures
Name Time Method Four items of blood lipid;urinary microalbumin;Number of patients with office blood pressure changed to normal blood pressure (SBP<120 mmHg/DBP<80 mmHg);24-hour mean blood pressure;SCORE Score of European Clinical Practice;rapid blood glucose;urinary albumin;glycosylated hemoglobin;diastolic blood pressure in office blood pressure;24-hour ambulatory blood pressure variability;urine beta-2 microglobulin;Number of people with SBP 135-144 mmHg or DBP 85-89 mmHg in Home BP;Number of admissions due to acute cardio-cerebrovascular attacks and new atrial fibrillation events;6 months ± 7 days;Number of patients with office blood pressure changed to SBP140-159 mmHg/DBP90-99 mmHg;