OPTIMIZATION of AVANCED MR SEQUENCES for BRAIN STUDIES in VOLUNTEERS (HEALTHY and PATIENTS)
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Enrollment
- 300
- Locations
- 1
- Primary Endpoint
- MR sequences optimization
Study Overview
Brief Summary
This monocentric methodological study aims at optimizing advanced MR sequences for image quality (reduced artefacts, signal to noise ratio, acquisition time, stability of quantitative measurements) on a new MR unit dedicated to research in clinical and cognitive neuroscience.
Detailed Description
Primary goal : Optimization of MR protocols and validation of acquisition parameters of advanced MR sequences on healthy volunteers or patients on a new 3T MR unit dedicated to research in neurosciences.
Secondary goals
- Perform acquisitions to validate the feasibility of research MR protocols (pilot subjects)
- reproducibility studies
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Other
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Covered by social security
- •For women in age of procreation, under efficient contraception
- •Written consent
Exclusion Criteria
- •Any MR contraindication
- •Claustrophobia
- •Pregnancy
- •Under judiciary protection
Outcomes
Primary Outcomes
MR sequences optimization
Time Frame: 72 months
Optimization of MR protocols and validation of acquisition parameters of advanced MR sequences on healthy volunteers or patients on a new 3T MR unit dedicated to research in neurosciences. Outcome measures depend on each pulse optimized sequence (signal-to-noise ratio, contrast-to-noise ratio, quantitative MR biomarkers).
Secondary Outcomes
- Reproducibility studies(72 months)
- Pilot studies(72 months)