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Clinical Trials/CTRI/2024/04/066171
CTRI/2024/04/066171Not yet recruitingNot Applicable

Doppler renal resistive index to predict risk of acute kidney injury in critically ill patients after abdominal surgery.

Department of Anesthesia and Intensive CareVMMC and Safdurjung hospital1 site in 1 country81 target enrollmentStarted: May 3, 2024Last updated:

Trial Snapshot

Phase
Not Applicable
Status
Not yet recruiting
Sponsor
Enrollment
81
Locations
1
Primary Endpoint
To assess the sensitivity and specificity of Doppler renal resistive index (RRI) for predicting risk of acute kidney injury in critically ill patients after abdominal surgery.

Study Overview

Brief Summary

Post operative AKI (PO-AKI) is defined as AKI onset within 7 days of surgery. PO-AKI is associated with a longer length of ICU stay, need for mechanical ventilation, higher risk of progression to chronic kidney disease (CKD) and ICU readmission rates. Doppler based renal resistive index (RRI) is a novel index derived from ultrasound scanning of interlobular or arcuate renal arteries at the cortico-medullary junction.. In general, RRI value of 0.6 is considered to be normal. RRI value above 0.7 is associated with development of high renal vascular resistance and may indicate development of AKI. Hence, this study was planned to predict the risk of AKI in critically ill patients after abdominal surgery using Doppler renal resistive index (RRI).

Study Design

Study Type
Observational

Eligibility Criteria

Ages
18.00 Year(s) to 60.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • 1.Age greater than 18 years.
  • 2.patients admitted in intensive care unit after abdominal surgery.
  • 3.At risk pateints for developing post operative acute kidney injury.

Exclusion Criteria

  • End stage renal disease with GFR less than 30/min/1.73 m2 BSA (Body Surface Area) 2.Cirrhosis with hepato – renal syndrome 3.Obstructive acute renal failure / Renal artery stenosis 4.Patients with cardiac arrythmias or haemodynamic instability (even with vasopressors) 5.Pregnancy.

Outcomes

Primary Outcomes

To assess the sensitivity and specificity of Doppler renal resistive index (RRI) for predicting risk of acute kidney injury in critically ill patients after abdominal surgery.

Time Frame: Renal Resistive Index is measured daily from Day1 to Day 7 after admission into Intensive Care Unit after abdominal surgery.

Secondary Outcomes

  • 1. To correlate RRI with eGFR.(2. To correlate RRI with 24 hour urine output.)

Investigators

Sponsor
Department of Anesthesia and Intensive CareVMMC and Safdurjung hospital
Sponsor Class
Government medical college
Responsible Party
Principal Investigator
Principal Investigator

Dr.Surishetty venkata sumanth

VMMC and Safdurjung hospital.

Study Sites (1)

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