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临床试验/CTRI/2024/04/066171
CTRI/2024/04/066171尚未招募不适用

Doppler renal resistive index to predict risk of acute kidney injury in critically ill patients after abdominal surgery.

Department of Anesthesia and Intensive CareVMMC and Safdurjung hospital1 个研究点 分布在 1 个国家目标入组 81 人开始时间: 2024年5月3日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
81
试验地点
1
主要终点
To assess the sensitivity and specificity of Doppler renal resistive index (RRI) for predicting risk of acute kidney injury in critically ill patients after abdominal surgery.

研究概览

简要总结

Post operative AKI (PO-AKI) is defined as AKI onset within 7 days of surgery. PO-AKI is associated with a longer length of ICU stay, need for mechanical ventilation, higher risk of progression to chronic kidney disease (CKD) and ICU readmission rates. Doppler based renal resistive index (RRI) is a novel index derived from ultrasound scanning of interlobular or arcuate renal arteries at the cortico-medullary junction.. In general, RRI value of 0.6 is considered to be normal. RRI value above 0.7 is associated with development of high renal vascular resistance and may indicate development of AKI. Hence, this study was planned to predict the risk of AKI in critically ill patients after abdominal surgery using Doppler renal resistive index (RRI).

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • 1.Age greater than 18 years.
  • 2.patients admitted in intensive care unit after abdominal surgery.
  • 3.At risk pateints for developing post operative acute kidney injury.

排除标准

  • End stage renal disease with GFR less than 30/min/1.73 m2 BSA (Body Surface Area) 2.Cirrhosis with hepato – renal syndrome 3.Obstructive acute renal failure / Renal artery stenosis 4.Patients with cardiac arrythmias or haemodynamic instability (even with vasopressors) 5.Pregnancy.

结局指标

主要结局

To assess the sensitivity and specificity of Doppler renal resistive index (RRI) for predicting risk of acute kidney injury in critically ill patients after abdominal surgery.

时间窗: Renal Resistive Index is measured daily from Day1 to Day 7 after admission into Intensive Care Unit after abdominal surgery.

次要结局

  • 1. To correlate RRI with eGFR.(2. To correlate RRI with 24 hour urine output.)

研究者

发起方
Department of Anesthesia and Intensive CareVMMC and Safdurjung hospital
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr.Surishetty venkata sumanth

VMMC and Safdurjung hospital.

研究点 (1)

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