Doppler renal resistive index to predict risk of acute kidney injury in critically ill patients after abdominal surgery.
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 81
- Locations
- 1
- Primary Endpoint
- To assess the sensitivity and specificity of Doppler renal resistive index (RRI) for predicting risk of acute kidney injury in critically ill patients after abdominal surgery.
Study Overview
Brief Summary
Post operative AKI (PO-AKI) is defined as AKI onset within 7 days of surgery. PO-AKI is associated with a longer length of ICU stay, need for mechanical ventilation, higher risk of progression to chronic kidney disease (CKD) and ICU readmission rates. Doppler based renal resistive index (RRI) is a novel index derived from ultrasound scanning of interlobular or arcuate renal arteries at the cortico-medullary junction.. In general, RRI value of 0.6 is considered to be normal. RRI value above 0.7 is associated with development of high renal vascular resistance and may indicate development of AKI. Hence, this study was planned to predict the risk of AKI in critically ill patients after abdominal surgery using Doppler renal resistive index (RRI).
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18.00 Year(s) to 60.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •1.Age greater than 18 years.
- •2.patients admitted in intensive care unit after abdominal surgery.
- •3.At risk pateints for developing post operative acute kidney injury.
Exclusion Criteria
- •End stage renal disease with GFR less than 30/min/1.73 m2 BSA (Body Surface Area) 2.Cirrhosis with hepato – renal syndrome 3.Obstructive acute renal failure / Renal artery stenosis 4.Patients with cardiac arrythmias or haemodynamic instability (even with vasopressors) 5.Pregnancy.
Outcomes
Primary Outcomes
To assess the sensitivity and specificity of Doppler renal resistive index (RRI) for predicting risk of acute kidney injury in critically ill patients after abdominal surgery.
Time Frame: Renal Resistive Index is measured daily from Day1 to Day 7 after admission into Intensive Care Unit after abdominal surgery.
Secondary Outcomes
- 1. To correlate RRI with eGFR.(2. To correlate RRI with 24 hour urine output.)
Investigators
Dr.Surishetty venkata sumanth
VMMC and Safdurjung hospital.