Postoperative Noninvasive Ventilation After Upper Abdominal Surgery in Chronic Obstructive Lung Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- acute respiratory events
研究概览
简要总结
In Qena university hospital a prospective, randomized study was carried out on 100 COPD patients, all were divided into; conventional therapy without NIV (C group) 50 patients or with prophylactic NIV(N group) 50 patients.NIV applied for approximately 30 to 45 min at 2- to 4-h intervals for 48 h following surgery . Primary endpoint was the acute respiratory events (ARE) .Secondary endpoints were acute respiratory failure (ARF), intubation rate, mortality rate, infectious and non-infectious complications, and ICU stay.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Inclusion criteria:
- •Age˃18 years, scheduled for upper abdominal surgery under general anesthesia.
- •Moderate to very severe COPD (GOLD II to IV).
- •ASA functional status II or greater.
排除标准
- •Contraindications to the application of NIV.
- •Sleep apnea syndrome.
- •Facial deformation.
- •Inability to follow the study.
研究组 & 干预措施
Group N
50 patients.NIV applied for approximately 30 to 45 min at 2- to 4-h intervals for 48 h following surgery
干预措施: NIV (Device)
group C
50 patients recieved conventional oxygen therpy.
结局指标
主要结局
acute respiratory events
时间窗: 28days
patients %
次要结局
- acute respiratory failure(28 days)
- intubation rate(28 days)
- ICU mortality(28 days)
- ICU length of stay(28 days)
- infectious and non infectious complications(28 days)
研究者
Asmaa Mohamed
PhD candidate _anesthesia ,ICU &pain management_Qena SVU
South Valley University