Study on treatment of traditional Chinese medicine of drug-induced liver injury: a randomized controlled trial.
- Conditions
- Drug-induced liver injury
- Registration Number
- ITMCTR2000003269
- Lead Sponsor
- Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1. Those who meet the diagnostic criteria for tuberculosis and have abnormal liver function after applying anti-tuberculosis drugs;
2. The severity of DILI is graded 1-2;
3. The age range is between 18-75 years old;
4. Not taking other drugs to protect liver and reduce enzyme, Or has been suspended for more than 2 weeks;
5. Signed informed consent voluntarily.
1. The liver function test before medication is elevated in alanine aminotransferase or bilirubin, and any of them is> 2 times the upper limit of normal value;
2. People with HIV infection, the original history of viral hepatitis or serological signs of hepatitis Those with positive substance;
3. Combined with serious primary diseases such as cardiocerebrovascular, kidney, hematopoietic system, peptic ulcer, or serious diseases (such as tumors) that affect their survival, or patients with mental or legal disabilities;
4. Do have a history of alcohol and drug abuse;
5. Allergic constitution, or known to be allergic to the drug components in the test protocol;
6. Pregnant, pregnant or lactating women.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method iver function;TCM syndrome points;Life quality assessment;
- Secondary Outcome Measures
Name Time Method Immune function test;Coagulation test;Renal function;