Changes in Biomarkers of Pain and Stress Perception After the Application of a Dry Needling Technique in Patients With Low Back Pain
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 36
- 试验地点
- 2
- 主要终点
- Extracting Blood Samples and Obtaining Serum/Plasma
研究概览
简要总结
The use of the dry needling technique has become widespread in recent years for the treatment of musculoskeletal pain. Although dry needling has been shown to be effective in the treatment of shoulder pain, elbow pain, headache, etc., we do not yet have a clear understanding of the mechanisms of action that justify its beneficial effects.
In this study, we propose to analyse the biochemical markers of pain generated by the application of a dry needling technique on the lumbar musculature in patients with mechanical lumbar pain of non-specific origin.
The aim of this study will be to evaluate the effects of dry needling technique on the plasmatic concentration of biochemical markers.Furthermore, the test subjects will be randomly distributed into two groups.
An experimental group where the subjects will receive a real dry needling technique.
Another group will be treated with a sham technique.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Mechanical lumbar pain of more than three months of evolution.
排除标准
- •Medical diagnosis of lumbar disc herniation or protrusion.
- •Low back and leg pain.
- •Pregnancy.
- •Fibromyalgia.
- •Fear of needles.
- •Medication with anticoagulants
结局指标
主要结局
Extracting Blood Samples and Obtaining Serum/Plasma
时间窗: Change from Baseline concentration at 2 hours
Serum samples will be extracted by venipuncture at the cubital fossa, according to a standardized protocol. Blood will be collected in a tube for serum (Vacutainer SST II Advance, model 367953) and a tube for plasma (Vacutainer PST II Advance, model 367374) separation. Substances related to antinociception will be determined later: Dopamine, adrenaline, norepinephrine, cortisol.
次要结局
未报告次要终点
研究者
Prof. Dr. Daniel Pecos Martín
Principal investigator
University of Alcala